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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

581 questions in 23 reviews · Implants and prosthodontics

current versions
No studies 87 · 15%Ungraded 388 · 66.8%Very low 88 · 15.1%Low 10 · 1.7%Moderate 8 · 1.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Osteotomes with mallet (Summers' technique) vs Rotary instruments (Cosci technique)
Complications · Patients undergoing crestal maxillary sinus lift · 3 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 7.86 [0.75, 82.13]1 study · 12 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Duration of overall treatment · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
SMD -0.25 [-0.62, 0.12]3 studies · 111 participantsLow
Pre-drilling mini-screw implant vs Self-drilling mini-screw implant
Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
RR 1.12 [0.91, 1.38]1 study · 62 participantsUngraded
Hand mallet (osteotomes) vs Electric mallet
Augmentation procedure failure · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about… · 19 months to 3 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Augmentation failures 0/40 versus 0/40; none.1 study · 80 participantsUngraded
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)
Bone gain · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 6 months after augmentation
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
MD 0.26 [-0.91, 1.43]1 study · 9 participantsUngraded
Dual mini-screw implant vs Single mini-screw implant
Mesiodistal movement of the upper first permanent molar · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
MD 1.62 [0.98, 2.26]1 study · 25 participantsUngraded
Steri-Oss acid-etched titanium screws vs Southern blasted/etched titanium screws
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 10 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 0.14 [0.02, 1.08]2 studies · 48 participantsUngraded
Southern regular implants vs Neoss turned implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 3.25 [0.15, 72.36]1 study · 23 participantsUngraded
NobelActive internal connection implants vs Nobel Speedy Groovy external connection implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures; risk ratio not estimable (Pozzi 2014)1 study · 34 participantsUngraded
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)
Bone gain · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 30 months after augmentation
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
MD 0.10 [-1.04, 1.24]1 study · 39 participantsUngraded
One-stage lateral sinus lift with monocortical autogenous bone blocks (iliac crest) vs Two-stage lateral sinus lift with autogenous particulate bone (iliac crest)
Prosthesis failure · Patients with 2 to 7 mm of residual alveolar bone height in the edentulous maxillary sinus floor · 3 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 1.00 [0.06, 17.18]1 study · 40 participantsUngraded
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)
Complications · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.50 [0.01, 9.60]1 study · 9 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Duration of space closure · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
SMD -0.09 [-0.54, 0.35]3 studies · 80 participantsUngraded
Rotary instruments to open the lateral sinus window vs Piezosurgery to open the lateral sinus window
Implant failure · Patients undergoing lateral-window maxillary sinus lift · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Rickert 2013 (N = 36): no implant failures in either group.1 study · 36 participantsUngraded
Astra TiO2-blast titanium implants vs SwissPlus (Zimmer) cylindrical implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 5 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures; risk ratio not estimable (Akoglu 2011)1 studyUngraded
Hand mallet (osteotomes) vs Electric mallet
Complications at augmented site · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about… · 19 months to 3 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 3.16 [0.31, 31.78]1 study · 80 participantsUngraded
Autogenous bone graft (two-stage lateral sinus lift) vs Bone substitute (anorganic bovine bone / Bio-Oss)
Implant failure · Patients with an atrophic posterior maxilla requiring maxillary sinus augmentation · abutment connection to 1 year
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 4.20 [0.81, 21.79]2 studies · 51 participantsUngraded
NobelActive external connection implants vs NobelActive internal connection implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 3 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 1.06 [0.25, 4.51]1 study · 113 participantsUngraded
Bone graft with platelet-rich plasma (PRP) vs Bone graft without PRP
Implant failure · Patients with insufficient bone below the maxillary sinus requiring dental implants · 2 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
No statistically significant difference for implant failures. Per trial: Raghoebar 2005 1 failure in the PRP arm, OR 3.67 (0.12 to 113.73), P = 0.46; Torres 2009 (PRP only = 1, no-PRP only = 2), OR 0.50 (0.01 to…2 studies · 62 participantsUngraded
NobelActive internal connection implants vs Nobel Speedy Groovy external connection implants
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD -0.59 [-0.74, -0.44]1 study · 34 participantsUngraded
Bone substitute (anorganic bovine bone / Bio-Oss) vs A different bone substitute
Prosthesis failure · Patients undergoing two-stage maxillary sinus augmentation · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Lindgren 2012 (split-mouth, 11 patients): prosthesis failures 0/11 versus 0/11; none.1 study · 11 participantsUngraded
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)
Augmentation procedure failure · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.48 [0.04, 5.67]1 study · 44 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Number of visits · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
MD 7.01 [3.47, 10.55]1 study · 47 participantsUngraded
Rotary instruments to open the lateral sinus window vs Piezosurgery to open the lateral sinus window
Complications at augmented site · Patients undergoing lateral-window maxillary sinus lift · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 1.00 [0.27, 3.74]1 study · 36 participantsUngraded
Dual mini-screw implant vs Single mini-screw implant
Patient acceptability · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
Acceptability was not reported in any of the studies comparing two types of surgical anchorage0 studiesNo studies
NobelActive internal connection implants vs NobelReplace implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 3 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 0.90 [0.25, 3.15]1 study · 106 participantsUngraded
One-stage augmentation (implants placed simultaneously) vs Two-stage augmentation (delayed implant placement)
Prosthesis failure · Patients requiring maxillary sinus augmentation · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.35 [0.01, 6.83]1 study · 58 participantsUngraded
Astra cylindrical turned surface implants vs Astra cylindrical TiO2-blasted surface implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 5 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
Primary pairwise data unusable (implant numbers per surface not disclosed); one turned implant failed early. Data used only for the turned-vs-roughened secondary analysis (Wennstrom 2004)1 study · 51 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Patient perception: pain · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
Reported narratively in 1 study (Feldmann 2007) on a VAS 0-100; the first evening after the intervention pain was significantly higher for surgical group A (P=0.002) and conventional group C (P=0.007) than surgical…1 study · 113 participantsUngraded
Pre-drilling mini-screw implant vs Self-drilling mini-screw implant
Patient perception: pain · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
Self-reported pain on insertion (0-4 scale): pre-drilling mean 0.73 (SD 1.1; median 0.00, IQR 0-3) vs self-drilling mean 1.87 (SD 1.13; median 2.0, IQR 0-4); 1 study (Lehnen 2011), 30 participants1 study · 30 participantsUngraded
WINSIX cylindrical implants vs WINSIX tapered implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 2 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 2.00 [0.38, 10.58]1 study · 132 participantsUngraded
Bone substitute (anorganic bovine bone / Bio-Oss) vs A different bone substitute
Complications at augmented site · Patients undergoing two-stage maxillary sinus augmentation · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 3.29 [0.12, 89.8]1 study · 11 participantsUngraded
Ankylos Plus (Dentsply) implants vs Seven (Sweden & Martina) implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures; risk ratio not estimable (Crespi 2009)1 study · 48 participantsUngraded
SPI Element sand-blasted acid-etched standard implants vs SPI Element SurfLink-modified implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures; risk ratio not estimable (Esposito 2013a)1 study · 23 participantsUngraded
One-stage augmentation (implants placed simultaneously) vs Two-stage augmentation (delayed implant placement)
Complications · Patients requiring maxillary sinus augmentation · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 2.23 [0.19, 26.06]1 study · 58 participantsUngraded
Astra TiO2-blast cylindrical implants vs Astra TiO2-blast conical (tapered, microthreaded) implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 3 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures; risk ratio not estimable (Lee 2007)1 study · 34 participantsUngraded
Hand mallet (osteotomes) vs Electric mallet
Prosthesis failure · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about… · 19 months to 3 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Crespi 2012 (parallel, 40 per group): prosthesis failures 0/40 versus 0/40; none.1 study · 80 participantsUngraded
One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long
Augmentation (graft) procedure failure · Patients with 3 to 6 mm of residual bone height at the sinus floor · 5 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.18 [0.01, 4.01]1 study · 40 participantsUngraded
ITI SLA cylindrical implants vs ITI SLA tapered implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures (Lang 2007, Table 2); risk ratio not estimable1 study · 208 participantsUngraded
Hand mallet (osteotomes) vs Electric mallet
Bone gain · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about… · after augmentation
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
MD 0.10 [-0.52, 0.72]1 study · 80 participantsUngraded
Southern wide implants vs Neoss turned implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures; risk ratio not estimable (Alsabeeha 2011)1 studyUngraded
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)
Implant failure · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.52 [0.10, 2.82]2 studies · 53 participantsUngraded
Dual mini-screw implant vs Single mini-screw implant
Adverse effects · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
Adverse effects were not reported in any of the studies comparing two types of surgical anchorage0 studiesNo studies
Branemark Mark II turned titanium screws vs ITI TPS hollow titanium screws
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 10 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 1.64 [0.22, 12.01]2 studies · 99 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Economic factors · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
No studies reported on economic evaluation0 studiesNo studies
MegaGen EZ Plus blasted standard implants vs MegaGen EZ Plus calcium-incorporated (Xpeed) implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures; risk ratio not estimable (Esposito 2012)1 study · 60 participantsUngraded
Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation
Prosthesis failure · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the… · median 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Peto OR 0.37 [0.05, 2.68]3 studies · 109 participantsModerate
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)
Bone gain · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 6 months after augmentation
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
MD 3.60 [2.99, 4.21]1 study · 41 participantsUngraded
Branemark Mark II standard titanium screws vs Branemark conical transmucosal titanium screws
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 2 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures in either group; risk ratio not estimable (Gatti 2002)1 study · 10 participantsUngraded
Bone graft with platelet-rich plasma (PRP) vs Bone graft without PRP
Partial graft loss · Patients with insufficient bone below the maxillary sinus requiring dental implants · 2 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 1.5 [0.17, 17.96]1 study · 57 participantsUngraded