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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,653 questions in 194 reviews · Gynaecology and Fertility
current versionsNo studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Sacral colpopexy: laparoscopic vs alternative approach Any complications (Clavien‐Dindo > 3) · women with apical vaginal prolapse Surgery for women with apical vaginal prolapse (2023) · Cochrane | RR 1.26 [0.17, 9.44] | 2 studies · 193 participants | Very low |
Sacral colpopexy: laparoscopic vs alternative approach Operating time (minutes) · women with apical vaginal prolapse Surgery for women with apical vaginal prolapse (2023) · Cochrane | no estimate extracted | 3 studies · 241 participants | Very low |
Sacral colpopexy: laparoscopic vs alternative approach Length of Hospital Stay (days) · women with apical vaginal prolapse Surgery for women with apical vaginal prolapse (2023) · Cochrane | no estimate extracted | 3 studies · 246 participants | Low |
Vaginal procedure vs sacral colpopexy (vault prolapse) Painful intercourse ‐ Dyspareunia · women with apical vaginal vault prolapse Surgery for women with apical vaginal prolapse (2023) · Cochrane | RR 3.44 [0.61, 19.53] | 3 studies · 106 participants | Low |
Vaginal procedure vs sacral colpopexy (vault prolapse) Operating time (minutes) · women with apical vaginal vault prolapse Surgery for women with apical vaginal prolapse (2023) · Cochrane | no estimate extracted | 6 studies · 517 participants | Low |
Vaginal procedure vs sacral colpopexy (vault prolapse) Cost (US dollars) · women with apical vaginal vault prolapse Surgery for women with apical vaginal prolapse (2023) · Cochrane | no estimate extracted | 2 studies · 188 participants | Low |
Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse) Awareness of prolapse · women with apical uterine prolapse Surgery for women with apical vaginal prolapse (2023) · Cochrane | RR 1.01 [0.1, 9.98] | 2 studies · 200 participants | Very low |
Summary of findings table ‐ Progestogens vs GnRH antagonists Live birth or ongoing pregnancy ‐ total · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 1 participants | Very low |
Summary of findings table ‐ Progestogens vs GnRH antagonists Premature LH surge ‐ Own oocytes ‐ PCOS (high‐responders) ‐ Early phase stimulation protocol ‐ Frozen embryo transfer · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 1 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Total oocytes ‐ Normoresponders ‐ Donor oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer (MPA 10 mg/day versus GnRH antagonists) · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 2 studies · 534 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Total oocytes ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 120 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists MII oocytes · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Total dose of gonadotropins (IU) ‐ total · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 4 studies · 952 participants | Moderate |
Summary of findings table ‐ Progestogens vs GnRH antagonists MII oocytes ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 120 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Moderate or severe OHSS ‐ total · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 3 studies · 3 participants | High |
Summary of findings table ‐ Progestogens vs GnRH antagonists Duration of stimulation (days) ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 120 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Total dose of gonadotropins (IU) ‐ Poor responders (MPA 10 mg versus GNrH antagoninsts ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 340 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Total dose of gonadotropins (IU) ‐ Normoresponders ‐ Donor oocytes ‐ Early ophase stimulation protocol ‐ Fresh embryo transfer (MPA 10 mg/day versus GnRH antagonists · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 2 studies · 492 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Oocyte pick‐up cancellation ‐ total · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.92 [0.42, 2.01] | 3 studies · 648 participants | Low |
Summary of findings table ‐ Progestogens vs GnRH antagonists Total dose of gonadotropins (IU) ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stumulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 120 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Moderate or severe OHSS ‐ Poor‐responders (MPA 10 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 1 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Moderate or severe OHSS ‐ Normoresponders ‐ Donor oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer (MPA 10 mg/day versus GnRH antagonists) · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 2 studies · 2 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Live birth or ongoing pregnancy sensitivity analysis ‐ Poor‐responders (MPA 10 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1.25 [0.73, 2.13] | 1 study · 340 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Live birth or ongoing pregnancy sensitivity analysis ‐ PCOS (high‐responders) ‐ own oocytes ‐ early phase stimulation protocol ‐ frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1.87 [0.89, 3.91] | 1 study · 120 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Live birth or ongoing pregnancy sensitivity analysis ‐ total · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 2 studies · 2 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Oocyte pick‐up cancellation sensitivity analysis ‐ Normoresponders (MPA 10 mg versus GnRH antagonists) ‐ Donor oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.84 [0.28, 2.55] | 2 studies · 534 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Oocyte pick‐up cancellation sensitivity analysis ‐ Normoresponders (micronised progesterone 200 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1 [0.33, 3.06] | 1 study · 114 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Oocyte pick‐up cancellation sensitivity analysis ‐ PCOS (high‐responders)(micronised progesterone 100 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.33 [0.01, 8.21] | 1 study · 120 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Oocyte pick‐up cancellation sensitivity analysis ‐ total · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.86 [0.4, 1.83] | 4 studies · 768 participants | Ungraded |
Summary of findings table ‐ Progestogens vs GnRH antagonists Clinical pregnancy ‐ Poor‐responders (MPA 10 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1.32 [0.81, 2.16] | 1 study · 340 participants | Low |
Summary of findings table ‐ Progestagen vs GnRH agonist Live birth or ongoing pregnancy · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.94 [0.58, 1.53] | 1 study · 260 participants | Low |
Summary of findings table ‐ Progestagen vs GnRH agonist Oocyte pick‐up cancellation · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1.36 [0.46, 4.02] | 1 study · 260 participants | Low |
Summary of findings table ‐ Progestagen vs GnRH agonist Clinical Pregnancy · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.88 [0.54, 1.44] | 1 study · 260 participants | Low |
Summary of findings table ‐ Progestagen vs GnRH agonist Miscarriage · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.49 [0.12, 2] | 1 study · 260 participants | Low |
Summary of findings table ‐ Progestagen vs GnRH agonist MII oocytes · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 260 participants | High |
Summary of findings table ‐ Progestagen vs GnRH agonist Total dose of gonadotropins (IU) · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 1 study · 260 participants | High |
Summary of findings table ‐ Progestagen vs GnRH agonist Moderate or severe OHSS · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.14 [0.01, 2.73] | 1 study · 260 participants | Very low |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Live birth rate · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 2 studies · 2 participants | Ungraded |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Oocyte pick‐up cancellation ‐ Normo‐responders (MPA 4 mg versus Micronised progesterone 100 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.81 [0.43, 1.53] | 1 study · 300 participants | Low |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Oocyte pick‐up cancellation ‐ Normo‐responders (MPA 4 mg versus MPA 10 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 2.27 [0.9, 5.74] | 1 study · 300 participants | Moderate |
Summary of findings table ‐ Progestogens vs GnRH antagonists Miscarriage ‐ total · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 2 studies · 2 participants | Very low |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Oocyte pick‐up cancellation ‐ Normo‐responders (MPA 4 mg versus Dydrogesterone 20 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1.19 [0.61, 2.34] | 1 study · 300 participants | Low |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Oocyte pick‐up cancellation ‐ Normo‐responders (MPA 10 mg versus Dydrogesterone 20 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1.49 [0.8, 2.8] | 1 study · 520 participants | Moderate |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Oocyte pick‐up cancellation ‐ Normo‐responders (Dydrogesterone 20 mg versus Micronised progesterone 100 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.65 [0.4, 1.06] | 2 studies · 550 participants | Moderate |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Oocyte pick‐up cancellation ‐ Normo‐responders (Micronised progesterone 100 mg versus Micronised progesterone 200mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 0.35 [0.09, 1.37] | 1 study · 150 participants | Very low |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Clinical pregnancy ‐ Normo‐responders (MPA 10 mg versus Dydrogesterone 20 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1.11 [0.79, 1.57] | 1 study · 520 participants | Moderate |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Miscarriage ‐ Miscarriage per randomised woman ‐ Normo‐responders (MPA 10 mg versus Dydrogesterone 20 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | OR 1.66 [0.68, 4.07] | 1 study · 520 participants | Low |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 MII oocytes · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Total dose of gonadotropins · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings table ‐ Progestogen 1 vs Progestogen 2 Moderate or severe OHSS · assisted reproduction technology cycles Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian… (2023) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |