Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

116 questions · 117 findings · 13 reviews · Schizophrenia

No studies found 24 · 20.5%GRADE not reported 14 · 12%Very low 20 · 17.1%Low 32 · 27.4%Moderate 27 · 23.1%High 0 · 0%

FLUPHENAZINE (ORAL) vs QUETIAPINE

Clinically important response (defined by study) ‐ short term (up to 12 weeks) decreased rate of BPRS score < 20% · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes clinically important response (defined by study) ‐ short term (up to… compared with QUETIAPINE (very low certainty).

1 finding from 1 review

COMPARISON 1. ARIPIPRAZOLE vs QUETIAPINE

Global state: No clinically significant response (as defined by the original studies) · patients with schizophrenia

COMPARISON 2. ARIPIPRAZOLE showed no clear difference in global state: No clinically significant response (as defined by… compared with QUETIAPINE (low certainty).

1 finding from 1 review