Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

117 questions · 123 findings · 16 reviews

No studies found 21 · 17.1%GRADE not reported 5 · 4.1%Very low 31 · 25.2%Low 30 · 24.4%Moderate 22 · 17.9%High 14 · 11.4%

Gram‐positive and gram‐negative coverage vs gram‐negative and anaerobic coverage

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐positive and gram‐negative coverage changes mortality compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Gram‐positive and gram‐negative coverage vs gram‐negative and anaerobic coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐positive and gram‐negative coverage changes intra‐abdominal infection compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐positive, gram‐negative, and anaerobic coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐positive, gram‐negative, and anaerobic coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

1 finding from 1 review