Severe (defined as stage 3 or greater) retinopathy of prematurity ‐ not reported · postoperative pain in preterm and term infants
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Severe (grade 3 or greater) intraventricular hemorrhage (IVH) on cranial ultrasound ‐ not reported · postoperative pain in preterm and term infants
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain (PIPP) · procedural pain in neonates
3 findings from 1 review
Parent satisfaction with care provided in the NICU—not reported · procedural pain in neonates
The review found no eligible studies for this question.
1 finding from 1 review
Pain, assessed using the DAN pain scale, ranging from 0 to 21, 1 to 2 hours after procedure · procedural pain in neonates
1 finding from 1 review
Pain, assessed using the CRIES pain scale, ranging from 0 to 10, during the procedure— opioids versus facilitated tucking · procedural pain in neonates
1 finding from 1 review
Any harms ‐ severe apnea requiring resuscitation · procedural pain in neonates
It is very uncertain whether opioids changes any harms ‐ severe apnea requiring resuscitation compared with no treatment/placebo (very low certainty).
1 finding from 1 review
Episodes of bradycardia · procedural pain in neonates
It is very uncertain whether opioids changes episodes of bradycardia compared with no treatment/placebo (very low certainty).
1 finding from 1 review
Episodes of apnea · procedural pain in neonates
Opioids may leads to higher episodes of apnea compared with no treatment/placebo (low certainty).
1 finding from 1 review
Hypotension · procedural pain in neonates
1 finding from 1 review
NFCS pain score during the procedure№ of infants: 112(2 RCTs) Score · procedural pain in neonates
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Pain score assessed up to 10 minutes after the procedure · procedural pain in neonates
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Episodes of bradycardia · procedural pain in neonates
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Episodes of apnea · procedural pain in neonates
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hypotension requiring medical therapy (vasopressors or fluid boluses), occurring during the procedure · procedural pain in neonates
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Successful LP on first attempt № of LPs: 100(1 quasi‐RCT) · lumbar puncture in newborn infants
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Total number of LP attempts № of LPs: 100(1 quasi‐RCT) · lumbar puncture in newborn infants
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Episodes of bradycardia · lumbar puncture in newborn infants
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
NFCS pain score during the procedure№ of infants: 112(2 RCTs) Score · lumbar puncture in newborn infants
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Episodes of desaturation, defined as a decrease of SpO2 to less than 80%, with no minimum duration specified—not reported · lumbar puncture in newborn infants
1 finding from 1 review
no estimate extracted
Studies not reported
Very low