Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

256 questions · 278 findings · 34 reviews · ENT

No studies found 86 · 30.9%GRADE not reported 1 · 0.4%Very low 88 · 31.7%Low 66 · 23.7%Moderate 35 · 12.6%High 2 · 0.7%

Intranasal steroid spray vs placebo or no intervention

Change in sense of smell · people with olfactory dysfunction for less than 4 weeks following COVID‐19 infection
3 findings from 1 review

Antibiotics vs no treatment or placebo on top of topical antibiotics

Ear pain (otalgia) or discomfort or local irritation · people (of any age) with CSOM

It is very uncertain whether systemic antibiotics changes ear pain (otalgia) or discomfort or local irritation ‐ measured at 1… compared with no treatment or placebo on top of topical antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs no treatment or placebo on top of topical antibiotics

Suspected ototoxicity · people (of any age) with CSOM

It is very uncertain whether systemic antibiotics changes suspected ototoxicity ‐ measured at 10 days to 3 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs no treatment or placebo on top of topical antibiotics

Resolution of ear discharge ‐ measured after 4 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

It is very uncertain whether systemic antibiotics changes resolution of ear discharge ‐ measured after 4 weeks (4 weeks)… compared with no treatment or placebo on top of topical antibiotics (very low certainty).

2 findings from 1 review

Antibiotics vs no treatment or placebo on top of topical antibiotics

Serious complications ‐ mastoid abscess measured at 12 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

It is very uncertain whether systemic antibiotics changes serious complications ‐ mastoid abscess measured at 12 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs no treatment or placebo on top of topical antiseptics

Resolution of ear discharge ‐ measured after 4 weeks · schoolchildren with CSOM

It is very uncertain whether systemic antibiotics changes resolution of ear discharge (4 weeks or more) ‐ measured at 3 to 4… compared with no treatment or placebo on top of topical antiseptics (very low certainty).

1 finding from 1 review