Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

215 questions · 236 findings · 28 reviews · Headline outcomes only

No studies found 45 · 19.1%GRADE not reported 15 · 6.4%Very low 78 · 33.1%Low 50 · 21.2%Moderate 34 · 14.4%High 14 · 5.9%

CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES

Mental state: General ‐ clinically important change (no improvement) · patients with schizophrenia

CBT showed no clear difference in mental state: General ‐ clinically important change (no improvement) compared with ALL OTHER PSYCHOLOGICAL THERAPIES (low certainty).

1 finding from 1 review

CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES

Satisfaction with treatment: leaving the study early Endpoint data (events) · patients with schizophrenia

CBT may leads to lower satisfaction with treatment ‐ leaving the study early for any reason compared with ALL OTHER PSYCHOLOGICAL THERAPIES (low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus TAC ‐ patient self‐assessment of scar improvement of 50% or higher, or patients considering the scar better or much better ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus TAC ‐ patient self‐assessment of… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC: sequelae ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC ‐ mild to moderate pain related to treatment ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus 5‐FU ‐ patient self‐assessment of… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus 5‐FU ‐ mild to moderate pain related to treatment ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus 5‐FU ‐ purpura ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ patient… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ mild to moderate pain related to treatment ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ purpura ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ 585‐nm PDL versus silicone gel sheeting ‐ skin irritation ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐ 585‐nm… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ erbium laser versus TAC ‐ patient self‐assessment ‐ patients considering the scar much better ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ erbium laser versus TAC ‐ patient self‐assessment ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ fractional carbon dioxide (CO2) laser versus TAC ‐ pain at injection site ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Incidence and severity of treatment‐related adverse effects ‐ fractional CO2 laser versus TAC ‐ telangectasia ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes incidence and severity of treatment‐related adverse effects ‐… compared with other treatments (very low certainty).

1 finding from 1 review