Findings

What do systematic reviews say?

108 questions · 109 findings · 17 reviews · Pain, Palliative and Supportive Care

No studies found 16 · 14.7%GRADE not reported 5 · 4.6%Very low 54 · 49.5%Low 9 · 8.3%Moderate 10 · 9.2%High 15 · 13.8%

At least 50% of maximum pain relief over 4 to 6 hours · adults with moderate or severe acute postoperative pain

The intervention leads to higher at least 50% of maximum pain relief over 4 to 6 hours (high certainty).

1 finding from 1 review

Single dose oral etoricoxib for acute postoperative pain in adults 2014 · Cochrane Headline outcomes only
RR 5.6 [4, 7.8]
Studies not reported
High

Participants with at least 1 adverse event · adults with moderate or severe acute postoperative pain

The intervention showed no clear difference in participants with at least 1 adverse event (moderate certainty).

1 finding from 1 review

Single dose oral etoricoxib for acute postoperative pain in adults 2014 · Cochrane Headline outcomes only
RR 0.93 [0.74, 1.2]
Studies not reported
Moderate

Participants with a serious adverse event · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral etoricoxib for acute postoperative pain in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Deaths · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral etoricoxib for acute postoperative pain in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

At least 50% of maximum pain relief over 4 to 6 hours · Adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral dexibuprofen [S(+)‐ibuprofen] for acute postoperative pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Participants with at least 1 adverse event · Adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral dexibuprofen [S(+)‐ibuprofen] for acute postoperative pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Participants with a serious adverse event · Adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral dexibuprofen [S(+)‐ibuprofen] for acute postoperative pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Deaths · Adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral dexibuprofen [S(+)‐ibuprofen] for acute postoperative pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low