Findings

What do systematic reviews say?

109 questions · 110 findings · 30 reviews · Musculoskeletal

No studies found 1 · 0.9%GRADE not reported 0 · 0%Very low 22 · 20%Low 56 · 50.9%Moderate 27 · 24.5%High 4 · 3.6%

Wrist fractures · postmenopausal women at lower risk of fractures1

The review found no eligible studies for this question.

1 finding from 1 review

Withdrawals due to adverse events · postmenopausal women at lower risk of fractures1

Intermittent/cyclic etidronate 400 mg/day showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Serious adverse events · postmenopausal women at lower risk of fractures1

Intermittent/cyclic etidronate 400 mg/day showed no clear difference in serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Clinical vertebral fractures · postmenopausal women at lower risk of fractures1

1 finding from 1 review

Non‐vertebral fractures · postmenopausal women at lower risk of fractures1

It is very uncertain whether risedronate 5 mg/day changes non‐vertebral fractures compared with placebo (very low certainty).

1 finding from 1 review

Hip Fracture · postmenopausal women at lower risk of fractures1

1 finding from 1 review

Wrist fractures · postmenopausal women at lower risk of fractures1

Risedronate 5 mg/day showed no clear difference in wrist fractures compared with placebo (low certainty).

1 finding from 1 review

Withdrawals due to adverse events · postmenopausal women at lower risk of fractures1

Risedronate 5 mg/day showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Serious adverse events · postmenopausal women at lower risk of fractures1

It is very uncertain whether risedronate 5 mg/day changes serious adverse events compared with placebo (very low certainty).

1 finding from 1 review