Findings

What do systematic reviews say?

108 questions · 112 findings · 9 reviews · Pain, Palliative and Supportive Care

No studies found 7 · 6.3%GRADE not reported 6 · 5.4%Very low 42 · 37.5%Low 40 · 35.7%Moderate 13 · 11.6%High 4 · 3.6%

Paracetamol vs placebo · patients with postoperative pain

It is very uncertain whether the intervention changes paracetamol vs placebo (very low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 0.64 [0.51, 0.8]
13 studies · 1037 participants
Very low

Propacetamol vs placebo · patients with postoperative pain

The intervention showed no clear difference in propacetamol vs placebo (low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 1.62 [0.75, 3.48]
3 studies · 377 participants
Low

Para/propacetamol vs NSAIDs see footnote1 · patients with postoperative pain

The intervention showed no clear difference in para/propacetamol vs NSAIDs see footnote1 (low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 1.01 [0.86, 1.18]
5 studies · 353 participants
Low

Paracetamol vs NSAIDs see footnote1 · patients with postoperative pain

It is very uncertain whether the intervention changes paracetamol vs NSAIDs see footnote1 (very low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 0.9 [0.72, 1.13]
2 studies · 130 participants
Very low

Propacetamol vs NSAIDs see footnote1 · patients with postoperative pain

It is very uncertain whether the intervention changes propacetamol vs NSAIDs see footnote1 (very low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 1.08 [0.86, 1.34]
3 studies · 223 participants
Very low

Paracetamol vs propacetamol see footnote1 · patients with postoperative pain

The intervention showed no clear difference in paracetamol vs propacetamol see footnote1 (moderate certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 0.98 [0.77, 1.24]
3 studies · 361 participants
Moderate

Para/propacetamol vs placebo see footnote1 · patients with postoperative pain

The intervention probably leads to higher para/propacetamol vs placebo see footnote1 (moderate certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 2.86 [2.1, 3.91]
10 studies · 1143 participants
Moderate

Paracetamol vs placebo see footnote1 · patients with postoperative pain

The intervention probably leads to higher paracetamol vs placebo see footnote1 (moderate certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 3.65 [2.15, 6.21]
6 studies · 532 participants
Moderate