Ear pain: timing not reported · sudden sensorineural hearing loss
Intratympanic corticosteroids probably leads to higher ear pain: timing not reportedf compared with systemic corticosteroids (moderate certainty).
1 finding from 1 review
Ear pain: at the time of injection · sudden sensorineural hearing loss
1 finding from 1 review
Relapse · patients with acute asthma
Intramuscular corticosteroids showed no clear difference in relapse compared with oral corticosteroids (low certainty).
3 findings from 1 review
RR 0.94 [0.72, 1.24]
9 studies · 804 participants
Low
RR 0.74 [0.51, 1.07]
7 studies · 742 participants
Moderate
RR 0.99 [0.74, 1.33]
5 studies · 556 participants
Low
Adverse events · patients with acute asthma
Intramuscular corticosteroids showed no clear difference in adverse events compared with oral corticosteroids (low certainty).
1 finding from 1 review
Health outcomes Peak expiratory flow readings (higher readings indicate better peak flow) · patients with acute asthma
1 finding from 1 review
Persistence of symptoms · patients with acute asthma
Intramuscular corticosteroids showed no clear difference in symptom persistence compared with oral corticosteroids (low certainty).
1 finding from 1 review
24‐hour beta agonist use · patients with acute asthma
Intramuscular corticosteroids showed no clear difference in 24‐hour beta agonist use compared with oral corticosteroids (low certainty).
1 finding from 1 review
Low birthweight · pregnant women
Mild/moderate topical corticosteroids may leads to lower low birth weight compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.9
55713 participants
Low
Preterm birth · pregnant women
Mild/moderate topical corticosteroids may leads to lower preterm delivery compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.88
55713 participants
Low
Foetal death · pregnant women
Mild/moderate topical corticosteroids may leads to lower foetal death compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.7
48749 participants
Low
Low Apgar score · pregnant women
Mild/moderate topical corticosteroids may leads to lower low Apgar score compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.73
8756 participants
Low
Congenital abnormality · pregnant women
Mild/moderate topical corticosteroids may leads to lower congenital abnormality compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.93
9263 participants
Low
Orofacial cleft · pregnant women
Mild/moderate topical corticosteroids may leads to lower orofacial cleft compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.95
38446 participants
Low
Clinical improvement (dichotomous) · active EoE patients
Corticosteroids may leads to higher clinical improvement (dichotomous) compared with placebo (low certainty).
1 finding from 1 review
Histological improvement (dichotomous) · inactive EoE patients
Corticosteroids probably leads to higher histological improvement (dichotomous) compared with placebo (moderate certainty).
1 finding from 1 review
Histological improvement (continuous) · inactive EoE patients
1 finding from 1 review
Endoscopic improvement (dichotomous) · inactive EoE patients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Endoscopic improvement (continuous) · inactive EoE patients
1 finding from 1 review
Withdrawals due to adverse events · inactive EoE patients
Corticosteroids may leads to lower withdrawals due to adverse events 12 to 50 weeks compared with placebo (low certainty).
1 finding from 1 review
Clinical improvement (continuous) · active EoE patients
1 finding from 1 review