Findings

What do systematic reviews say?

106 questions · 113 findings · 11 reviews

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No studies found 21 · 18.6%GRADE not reported 29 · 25.7%Very low 29 · 25.7%Low 18 · 15.9%Moderate 15 · 13.3%High 1 · 0.9%

QUETIAPINE vs CLOZAPINE ‐ all data short term

Mental state · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 232 participants
Low

QUETIAPINE vs CLOZAPINE ‐ all data short term

Mental state: 2. Positive symptoms ‐ average endpoint score PANSS positive subscore · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 142 participants
Low

ZOTEPINE vs CLOZAPINE

Mental state: psychopathology Total endpoint data, BPRS (higher score = worse, scale from: 0‐126) · patients with schizophrenia

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

ZOTEPINE vs CLOZAPINE

Global state: No clinically important response (as defined by the original studies) · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes global state: No clinically important response (as defined by the… compared with CLOZAPINE (very low certainty).

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
RR 8.23 [1.14, 59.17]
1 study · 59 participants
Very low

ZOTEPINE vs CLOZAPINE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with CLOZAPINE (very low certainty).

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
RR 20.96 [2.89, 151.9]
2 studies · 116 participants
Very low

ZOTEPINE vs CLOZAPINE

Behaviour: No clinically important response (as defined by the original studies) · patients with schizophrenia

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported