Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,359 questions · 2,491 findings · 249 reviews

No studies found 696 · 27.9%GRADE not reported 213 · 8.6%Very low 611 · 24.5%Low 595 · 23.9%Moderate 315 · 12.6%High 61 · 2.4%

Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American

Abstinence at end of treatment ‐ homozygous major · people who smoke

Active NRT leads to higher abstinence at end of treatment ‐ homozygous major compared with placebo ‐ rs16969968 ‐ non‐Hispanic black or African American (high certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American

Abstinence at end of treatment ‐ heterozygous or homozygous minor · people who smoke

Active NRT probably leads to lower abstinence at end of treatment ‐ heterozygous or homozygous minor compared with placebo ‐ rs16969968 ‐ non‐Hispanic black or African American (moderate certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs1051730 ‐ non‐Hispanic white

Abstinence at end of treatment ‐ homozygous major · people who smoke

Active NRT showed no clear difference in abstinence at end of treatment ‐ homozygous major compared with placebo ‐ rs1051730 ‐ non‐Hispanic white (low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American

6‐Month abstinence ‐ homozygous major · people who smoke

It is very uncertain whether active NRT changes 6‐Month abstinence ‐ homozygous major compared with placebo ‐ rs2036527 ‐ non‐Hispanic black or African American (very low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American

6‐Month abstinence ‐ heterozygous or homozygous minor · people who smoke

Active NRT showed no clear difference in 6‐Month abstinence ‐ heterozygous or homozygous minor compared with placebo ‐ rs2036527 ‐ non‐Hispanic black or African American (moderate certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American

End of treatment ‐ homozygous major · people who smoke

Active NRT showed no clear difference in end of treatment ‐ homozygous major compared with placebo ‐ rs2036527 ‐ non‐Hispanic black or African American (low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American

End of treatment ‐ heterozygous or homozygous minor · people who smoke

Active NRT showed no clear difference in end of treatment ‐ heterozygous or homozygous minor compared with placebo ‐ rs2036527 ‐ non‐Hispanic black or African American (moderate certainty).

1 finding from 1 review

Active NRT vs placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white

6‐Month abstinence ‐ homozygous major · people who smoke

It is very uncertain whether active NRT changes 6‐month abstinence ‐ homozygous major compared with placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white (very low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white

6‐Month abstinence ‐ heterozygous · people who smoke

Active NRT showed no clear difference in 6‐Month abstinence ‐ heterozygous compared with placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white (low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white

6‐Month abstinence ‐ homozygous minor · people who smoke

It is very uncertain whether active NRT changes 6‐Month abstinence ‐ homozygous minor compared with placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white (very low certainty).

1 finding from 1 review

Active NRT vs placebo ‐ rs1051730 ‐ non‐Hispanic white

Abstinence at end of treatment ‐ heterozygous · people who smoke

Active NRT probably leads to higher abstinence at end of treatment ‐ heterozygous compared with placebo ‐ rs1051730 ‐ non‐Hispanic white (moderate certainty).

1 finding from 1 review

Active NRT vs placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white

End of treatment ‐ homozygous major · people who smoke

It is very uncertain whether active NRT changes end of treatment ‐ homozygous major compared with placebo ‐ DRD4 (exon 3 48 bp) ‐ non‐Hispanic white (very low certainty).

1 finding from 1 review