Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

115 questions · 115 findings · 11 reviews

No studies found 27 · 23.5%GRADE not reported 2 · 1.7%Very low 34 · 29.6%Low 33 · 28.7%Moderate 16 · 13.9%High 3 · 2.6%

Intervention not reported

ABC ‐ Irritability subscale Mean score changes 8 weeks of treatment · children/youth with ASD
1 finding from 1 review

Intervention not reported

ABC ‐ Hyperactivity subscale Mean score changes 8 weeks of treatment · children/youth with ASD
1 finding from 1 review

Intervention not reported

ABC ‐ Stereotypy subscale Mean score changes 8 weeks of treatment · children/youth with ASD
1 finding from 1 review

Intervention not reported

Weight gain 8 weeks of treatment · children/youth with ASD
1 finding from 1 review

Intervention not reported

Sedation 8 weeks of treatment · children/youth with ASD
1 finding from 1 review

Intervention not reported

Tremor 8 weeks of treatment · children/youth with ASD
1 finding from 1 review

Intervention not reported

Relapse rate 16 weeks of treatment · children/youth with ASD
1 finding from 1 review

Intervention not reported

Poor compliance with study protocol · people with schizophrenia or like psychosis

The intervention may leads to lower poor compliance with study protocol (low certainty).

1 finding from 1 review

Intervention not reported

Relapse · people with schizophrenia or like psychosis

The intervention may leads to lower relapse (low certainty).

1 finding from 1 review

Intervention not reported

Weight gain (equal or greater then 7% of baseline) · people with schizophrenia or like psychosis

The intervention may leads to higher weight gain (equal or greater then 7% of baseline) (low certainty).

1 finding from 1 review

Intervention not reported

Concomitant medication (Anxiolytic ‐ Lorazepam) · people with schizophrenia or like psychosis

The intervention may leads to lower concomitant medication (Anxiolytic ‐ Lorazepam) (low certainty).

1 finding from 1 review