BM‐MNCs vs mPBSCs
- Autologous cells derived from different sources and administered using different regimens for 'no‐option' critical… 2018 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 202 participantsGRADE not reported
It is very uncertain whether high cell dose changes amputation rate Assessed during in‐patient stay (Losordo 2012) compared with low cell dose (very low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
BM‐MNCs showed no clear difference in amputation rate Assessed during in‐patient stay compared with mPBSCs (low certainty).
IM injection showed no clear difference in amputation rate Assessed during in‐patient stay compared with IA injection (low certainty).
IM injection showed no clear difference in wound/ulcer healing: number of participants with healing ulcer compared with IA injection (low certainty).
IM injection showed no clear difference in reduction in rest pain: number of participants with reduction in… compared with IA injection (low certainty).
BM‐MNCs showed no clear difference in wound/ulcer healing: number of participants with healing ulcers… compared with mPBSCs (low certainty).
BM‐MNCs showed no clear difference in reduction in rest pain: number of participants with any reduction in… compared with mPBSCs (moderate certainty).
BM‐MNCs probably leads to higher wound/ulcer healing: number of participants with healing ulcers compared with BM‐MSCs (moderate certainty).
Low molecular weight heparin probably leads to lower deep venous thrombosis compared with no prophylaxis or placebo (moderate certainty).
Low molecular weight heparin showed no clear difference in pulmonary embolism compared with no prophylaxis or placebo (low certainty).
Low molecular weight heparin may leads to lower symptomatic venous thromboembolism compared with no prophylaxis or placebo (low certainty).