Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,703 questions · 3,824 findings · 858 reviews

No studies found 573 · 15%GRADE not reported 383 · 10%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Intervention not reported

Anthropometric outcomes: MUAC gain per day Defined as (discharge MUAC − admission MUAC)/days in treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting
1 finding from 1 review

Intervention not reported

Anthropometric outcomes: median weight gain per day (g/kg/d) Defined as ((discharge weight − admission weight)/weight on admission)/days on treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting
1 finding from 1 review

Intervention not reported

Transfer to inpatient care Defined as referral for: presence of danger signs and failed appetite test on first day of treatment (Alvarez Moran 2018)b; appearance of severe signs of illness, persistent oedema, absence of weight gain in non‐oedemato... · children aged > 6 months and < 5 years with wasting

It is very uncertain whether the intervention changes transfer to inpatient care Defined as referral for: presence of… (very low certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: weight gain per day (g/kg/day) Calculated as ((discharge weight − admission weight)/weight on admission)/days in treatment among recovered children (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting
1 finding from 1 review

Intervention not reported

All‐cause mortality at day 28 · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The intervention may leads to lower all‐cause mortality at day 28 (low certainty).

1 finding from 1 review

Intervention not reported

Viral clearance at 14 days · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

All‐cause mortality at day 28 · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

It is very uncertain whether the intervention changes all‐cause mortality at day 28 (very low certainty).

1 finding from 1 review

Intervention not reported

Quality of life up to 28 days and longest · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Viral clearance at 7 days · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

It is very uncertain whether the intervention changes viral clearance at 7 days (very low certainty).

1 finding from 1 review

Intervention not reported

Viral clearance at 14 days · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

It is very uncertain whether the intervention changes viral clearance at 14 days (very low certainty).

1 finding from 1 review

Intervention not reported

All initial symptoms resolved at 28 days, and up to the longest · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life up to 28 days and longest · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The review found no eligible studies for this question.

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Rate of orthodontic tooth movement during space closure stage (maxillary canine distalisation), mm/day · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether light-emitting diode (LED) photobiomodulation changes rate of orthodontic tooth movement during space closure stage… compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Neocone vs Alvogyl

Mean time to resolution of pain · Adults (>18 years) with established dry socket following permanent tooth extraction

Neocone led to lower time to complete resolution of pain (days) compared with alvogyl; GRADE not reported.

1 finding from 1 review