Findings

What do systematic reviews say?

4,411 questions · 5,986 findings · 226 reviews · Oral Health

Sort:Best matchNewestHighest certainty Download CSV

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

COE with vital rinsing (toluidine blue/tolonium chloride) vs Conventional oral examination (COE) alone

Sensitivity (COE alone arm) · Oral cavity cancer or potentially malignant disorder symptom-free individuals with tobacco habits

1 finding from 1 review

Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy… 2021 · Cochrane All outcomes
Sensitivity 0.50 [0.12, 0.88]
1 study · 3895 participants
Moderate

Rubber dam vs Isolite system

Restoration survival · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)

The review found no eligible studies for this question.

1 finding from 1 review

Rubber dam isolation for restorative treatment in dental patients 2021 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

ARP with alloplast vs ARP with xenograft

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast changes implant failure rate compared with ARP with xenograft (very low certainty).

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 to 8 months
Not estimable; 1 trial (Patel 2013) reported that none of the implants failed after 12 months of loading
1 study · 25 participants
Very low

COE with vital rinsing (toluidine blue/tolonium chloride) vs Conventional oral examination (COE) alone

Sensitivity · Oral cavity cancer or potentially malignant disorder symptom-free individuals with tobacco habits

1 finding from 1 review

Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy… 2021 · Cochrane All outcomes
Sensitivity 0.40 [0.05, 0.85]
1 study · 4080 participants
Moderate

Transillumination and optical coherence tomography devices (all illumination devices combined: NIR, OCT, and FOTI/DIFOTI) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

1 finding from 1 review

Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)
Sensitivity 0.75 [0.62, 0.85]
23 studies
Low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

Trismus (dichotomous, 7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes trismus (dichotomous, 7th day) compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes
7th day
RR 0.77 [0.42, 1.41]
3 studies · 199 participants
Very low

Super ethoxybenzoic acid (Super-EBA) vs Intermediate restorative material (IRM)

Adverse events · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…

The review found no eligible studies for this question.

1 finding from 1 review

Materials for retrograde filling in root canal therapy 2021 · Cochrane All outcomes
Adverse events: outcome was not assessed by the included studies
0 studies
No studies found

Mouth self-examination (MSE) vs Reference standard: examination and clinical evaluation by a physician/clinician with specialist knowledge or training (long-term follow-up accepted for those screened negative)

Sensitivity for detection of oral cavity cancer/OPMD · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…

1 finding from 1 review

Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy… 2021 · Cochrane All outcomes
Summary of findings 2 (no pooled analysis): sensitivity 0.18 (95% CI 0.13 to 0.24), 0.09 (95% CI 0.04 to 0.15), 0.43 (95% CI 0.24 to 0.63), and 0.33 (95% CI 0.10 to 0.65) across the 4 studies. Prevalence 0.6% to 63.6%.…
4 studies · 35059 participants
Very low

Removable tooth-borne expansion (expansion plate) vs observation

Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Removable tooth-borne expansion (expansion plate) probably leads to higher canine expansion (inter-canine distance) compared with observation (no treatment) (moderate certainty).

1 finding from 1 review

Orthodontic treatment for posterior crossbites 2021 · Cochrane All outcomes
Children (7 to 11 years)
MD 2.59 [2.18, 3.01]
3 studies · 145 participants
Moderate

Fixed tooth-bone-borne expansion vs Fixed tooth-borne expansion (Hyrax)

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-bone-borne expansion showed no clear difference in molar expansion (inter-molar distance) compared with fixed tooth-borne expansion (Hyrax) (low certainty).

1 finding from 1 review

Orthodontic treatment for posterior crossbites 2021 · Cochrane All outcomes
Children
MD 0.66 [-0.04, 1.36]
2 studies · 65 participants
Low

ARP with allograft (bone graft) vs ARP with xenograft

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 months
Outcome not reported
0 studies
No studies found

Lower lingual arch vs No active treatment (control)

Lower molars to mandible (relationship of lower back teeth to the mandible) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Lower lingual arch led to lower lower molars to mandible at 1 year compared with no active treatment (control); GRADE not reported.

1 finding from 1 review

Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
1 year
MD -1.11 [-1.51, -0.71]
1 study · 30 participants
GRADE not reported

Fixed tooth-borne expansion (quad-helix) vs Removable tooth-borne expansion (expansion plate)

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-borne expansion (quad-helix) probably leads to higher crossbite correction compared with removable tooth-borne expansion (expansion plate) (moderate certainty).

1 finding from 1 review

Orthodontic treatment for posterior crossbites 2021 · Cochrane All outcomes
Children (7 to 11 years)
RR 1.29 [1.13, 1.46]
3 studies · 151 participants
Moderate

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Overall treatment time wearing orthodontic appliances · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 months
Outcome not reported
0 studies
No studies found

Multistranded stainless steel archwire vs Stainless steel archwire

Amount of crowding (change in mandibular crowding) at 8 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether multistranded stainless steel archwire changes amount of crowding (change in mandibular crowding) at 8 weeks compared with stainless steel archwire (very low certainty).

1 finding from 1 review

Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
8 weeks
MD -18.40 [-47.12, 10.32]
1 study · 23 participants
Very low

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

Number of participants referred for surgical exposure of the PDC · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

It is very uncertain whether extraction of the primary (baby) canine (single primary tooth… changes number of participants referred for surgical exposure of the PDC compared with no extraction (non-intervention control) (very low certainty).

1 finding from 1 review

Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
12 months
RR 0.61 [0.29, 1.28]
1 study · 45 participants
Very low

Cervical pull headgear vs Minor interceptive procedures (control)

Lower incisors to mandible (relationship of lower front teeth to the mandible) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear showed no clear difference in lower incisors to mandible at 2 years compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review

Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
2 years
MD 1.4 [-0.42, 3.22]
1 study · 64 participants
GRADE not reported

Hall technique vs Non-restorative cavity control (NRCC)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

It is very uncertain whether hall Technique (sealing with a preformed metal crown) changes failure of therapy compared with non-restorative cavity control (NRCC) (very low certainty).

1 finding from 1 review

Interventions for treating cavitated or dentine carious lesions 2021 · Cochrane All outcomes
30 months · Cavitated lesions, primary dentition
OR 0.19 [0.05, 0.74]
1 study · 84 participants
Very low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo

Outcome not reported · Immunosuppressed / immunocompromised patients (e.g. HIV infection, AIDS, diabetes, transplants) undergoing tooth extraction

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes
No studies: none of the 23 included trials evaluated tooth extraction in immunocompromised patients; subgroup analysis based on immune status was not possible as no such studies were identified.
0 studies
No studies found