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Evidence found and GRADE certainty

1,133 questions · 1,153 findings · 36 reviews · Skin

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No studies found 407 · 35.3%GRADE not reported 90 · 7.8%Very low 183 · 15.9%Low 209 · 18.1%Moderate 211 · 18.3%High 53 · 4.6%

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

Proportion of participants who reported an adverse event · women with hirsutism

It is very uncertain whether flutamide 250 mg once to twice daily changes proportion of participants who reported an adverse event compared with metformin 1275 mg to 1700 mg per day (very low certainty).

1 finding from 1 review

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

Participant‐reported improvement of hirsutism 4‐point Likert scale · women with hirsutism

Finasteride 5 mg showed no clear difference in participant‐reported improvement of hirsutism 4‐point Likert scale compared with flutamide 250 mg once to b.i.d. (low certainty).

1 finding from 1 review

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

Proportion of participants who reported an adverse event · women with hirsutism

It is very uncertain whether finasteride 5 mg changes proportion of participants who reported an adverse event compared with flutamide 250 mg once to b.i.d. (very low certainty).

1 finding from 1 review