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Evidence found and GRADE certainty

1,352 questions · 1,400 findings · 169 reviews

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No studies found 309 · 22.1%GRADE not reported 115 · 8.2%Very low 350 · 25%Low 324 · 23.1%Moderate 240 · 17.1%High 62 · 4.4%

Oral azithromycin vs control

Active trachoma · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Anaerobic coverage only vs gram‐positive and gram‐negative coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐positive and gram‐negative coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐positive and gram‐negative coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐positive and gram‐negative coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐negative and anaerobic coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐negative and anaerobic coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Gram‐negative and anaerobic coverage vs gram‐positive, gram‐negative, and anaerobic coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐negative and anaerobic coverage changes abdominal surgical site infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

1 finding from 1 review

Gram‐negative and anaerobic coverage vs gram‐positive, gram‐negative, and anaerobic coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐negative and anaerobic coverage changes intra‐abdominal infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

1 finding from 1 review

Gram‐positive and gram‐negative coverage vs gram‐negative and anaerobic coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐positive and gram‐negative coverage changes abdominal surgical site infection compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Gram‐positive and gram‐negative coverage vs gram‐negative and anaerobic coverage

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐positive and gram‐negative coverage changes mortality compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Gram‐positive and gram‐negative coverage vs gram‐negative and anaerobic coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐positive and gram‐negative coverage changes intra‐abdominal infection compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐positive, gram‐negative, and anaerobic coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐positive, gram‐negative, and anaerobic coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

1 finding from 1 review

Azithromycin vs doxycycline

Microbiological failure Men · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

Azithromycin probably leads to higher microbiological failure Men compared with doxycycline (moderate certainty).

1 finding from 1 review

Doxycycline vs quinolones

Microbiological failure Men and women Doxycycline 100 mg twice a day for 7 days vs ofloxacin 300 mg once a day for 7 days · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…
1 finding from 1 review

Doxycycline vs quinolones

Adverse events (Analysis 1.7) Participant's report · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

It is very uncertain whether doxycycline changes adverse events Men and women Assessed by participants' self‐report compared with quinolones (very low certainty).

1 finding from 1 review