Findings

What do systematic reviews say?

1,310 questions · 1,358 findings · 214 reviews

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No studies found 230 · 16.9%GRADE not reported 169 · 12.4%Very low 269 · 19.8%Low 277 · 20.4%Moderate 291 · 21.4%High 122 · 9%

MAL‐PDT vs red light only

Investigator‐assessed change in non‐inflamed lesions (NILs) Lesion counts · Moderate and severe acne vulgaris

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 360 participants
Moderate

MAL‐PDT vs red light only

Investigator‐assessed percentage change in ILs Lesion counts · Moderate and severe acne vulgaris

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 360 participants
Moderate

MAL‐PDT vs red light only

Investigator‐assessed percentage change in NILs Lesion counts · Moderate and severe acne vulgaris

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 360 participants
Moderate

MAL‐PDT vs red light only

Investigator‐assessed severe adverse effects Application site blister · Moderate and severe acne vulgaris

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 360 participants
Moderate

Very tight vs tight‐moderate glycaemic control (infant outcomes)

Pre‐eclampsia · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Very tight vs tight‐moderate glycaemic control (infant outcomes)

Serious perinatal morbidity · pregnant women with pre‐existing type 1 diabetes

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Low

Very tight vs tight‐moderate glycaemic control (infant outcomes)

Neonatal hypoglycaemia · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Very tight vs tight‐moderate glycaemic control (infant outcomes)

Childhood/adulthood adiposity · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Very tight vs tight‐moderate glycaemic control (infant outcomes)

Childhood/adulthood diabetes · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Very tight vs tight‐moderate glycaemic control (infant outcomes)

Neurosensory disability · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tight vs moderate glycaemic control (maternal outcomes)

Pre‐eclampsia · pregnant women with pre‐existing type 1 diabetes

It is very uncertain whether tight changes pre‐eclampsia compared with moderate glycaemic control (maternal outcomes) (very low certainty).

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
RR 5.29 [0.23, 122.91]
1 study · 45 participants
Very low

Tight vs moderate glycaemic control (maternal outcomes)

Caesarean section · pregnant women with pre‐existing type 1 diabetes

It is very uncertain whether tight changes caesarean section compared with moderate glycaemic control (maternal outcomes) (very low certainty).

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
RR 1.21 [0.22, 6.5]
1 study · 45 participants
Very low

Tight vs moderate glycaemic control (maternal outcomes)

Perineal trauma · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tight vs moderate glycaemic control (maternal outcomes)

Gestational weight gain · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tight vs moderate glycaemic control (maternal outcomes)

Postnatal depression · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Very tight vs tight‐moderate glycaemic control (infant outcomes)

Caesarean section · pregnant women with pre‐existing type 1 diabetes

It is very uncertain whether very tight changes caesarean section compared with tight‐moderate glycaemic control (maternal outcomes) (very low certainty).

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
RR 0.92 [0.49, 1.73]
1 study · 22 participants
Very low

Tight vs moderate glycaemic control (maternal outcomes)

Induction of labour · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tight vs moderate glycaemic control (maternal outcomes)

Later development of cardiovascular disease · pregnant women with pre‐existing type 1 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tight vs moderate glycaemic control (infant outcomes)

Large‐for‐gestational age · pregnant women with pre‐existing type 1 diabetes

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Very low

Tight vs moderate glycaemic control (infant outcomes)

Perinatal mortality · pregnant women with pre‐existing type 1 diabetes

1 finding from 1 review

Different intensities of glycaemic control for pregnant women with pre‐existing diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Very low