All‐cause mortality · individuals with sickle cell disease who have had a stroke who have had long‐term red cell transfusions to prevent another stroke
It is very uncertain whether long‐term red cell transfusion changes all‐cause mortality compared with hydroxyurea and phlebotomy (very low certainty).
1 finding from 1 review
Adverse events associated with transfusion · individuals with sickle cell disease who have had a stroke who have had long‐term red cell transfusions to prevent another stroke
1 finding from 1 review
Incidence of TIA · individuals with sickle cell disease who have had a stroke who have had long‐term red cell transfusions to prevent another stroke
It is very uncertain whether long‐term red cell transfusion changes incidence of TIA compared with hydroxyurea and phlebotomy (very low certainty).
1 finding from 1 review
Serious adverse events as a result of sickle cell‐related complications · individuals with sickle cell disease who have had a stroke who have had long‐term red cell transfusions to prevent another stroke
It is very uncertain whether long‐term red cell transfusion changes serious adverse events as a result of sickle cell‐related… compared with hydroxyurea and phlebotomy (very low certainty).
1 finding from 1 review
Measures of neurological impairment ‐ not reported · individuals with sickle cell disease who have had a stroke who have had long‐term red cell transfusions to prevent another stroke
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life ‐ not reported · individuals with sickle cell disease who have had a stroke who have had long‐term red cell transfusions to prevent another stroke
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events associated with transfusion · individuals with sickle cell disease who are at risk of a primary stroke who have not had previous long‐term red cell transfusions
It is very uncertain whether long‐term red cell transfusion changes adverse events associated with transfusion compared with no transfusion (very low certainty).
1 finding from 1 review
TIA · individuals with sickle cell disease who are at risk of a primary stroke who have not had previous long‐term red cell transfusions
It is very uncertain whether long‐term red cell transfusion changes TIA compared with no transfusion (very low certainty).
1 finding from 1 review
Serious adverse events as a result of sickle cell‐related complications · individuals with sickle cell disease who are at risk of a primary stroke who have not had previous long‐term red cell transfusions
Long‐term red cell transfusion may leads to lower serious adverse events as a result of sickle cell‐related… compared with no transfusion (low certainty).
1 finding from 1 review
Neurological impairment · individuals with sickle cell disease who are at risk of a primary stroke who have not had previous long‐term red cell transfusions
1 finding from 1 review
Quality of life · individuals with sickle cell disease who are at risk of a primary stroke who have not had previous long‐term red cell transfusions
1 finding from 1 review
Stroke · individuals with sickle cell disease who are at risk of a primary stroke who have had long‐term red cell transfusions to prevent a stroke
It is very uncertain whether long‐term red cell transfusion changes clinical stroke compared with no transfusion (very low certainty).
1 finding from 1 review
All‐cause mortality · individuals with sickle cell disease who are at risk of a primary stroke who have had long‐term red cell transfusions to prevent a stroke
It is very uncertain whether long‐term red cell transfusion changes all‐cause mortality compared with no transfusion (very low certainty).
1 finding from 1 review
Intervention not reported
All‐cause mortality Median · individuals without known diabetes mellitus but at high risk for the condition
The intervention showed no clear difference in all‐cause mortality Median (low certainty).
1 finding from 1 review
Intervention not reported
Diabetes‐related mortality Assessed according to whether diabetes was included anywhere on the death certificate · individuals without known diabetes mellitus but at high risk for the condition
The intervention showed no clear difference in diabetes‐related mortality Assessed according to whether diabetes… (low certainty).
1 finding from 1 review
Intervention not reported
Diabetes‐related morbidity · individuals without known diabetes mellitus but at high risk for the condition
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Incidence of type 2 diabetes · individuals without known diabetes mellitus but at high risk for the condition
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Health‐related quality of life · individuals without known diabetes mellitus but at high risk for the condition
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Adverse events · individuals without known diabetes mellitus but at high risk for the condition
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Socioeconomic effects · individuals without known diabetes mellitus but at high risk for the condition
The review found no eligible studies for this question.
1 finding from 1 review