Gingivitis · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified
1 finding from 1 review
Electric vs manual toothbrush. Assorted gingival indices scale 0-4, 2-4 weeks; 252 participants (4 RCTs); Low. Four studies showed no significant differences for gingival inflammation short term; data could not be…
4 studies · 252 participants
Low
Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Topical G32 (ayurvedic preparation) showed no clear difference in volatile sulphur compounds (VSC) compared with chlorhexidine digluconate 1% gel; GRADE not reported.
1 finding from 1 review
Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
The review found no eligible studies for this question.
1 finding from 1 review
Gingivitis · Children aged 7 to 13 years with Down syndrome (mild to moderate ID); setting residential
1 finding from 1 review
Toothpaste with a plaque-disclosing agent vs conventional toothpaste, children with Down syndrome. Ainamo & Bay Gingival Bleeding Index, mean 10 days; percent mean difference 18 (intervention) vs 8 (control), P<0.001…
1 study · 40 participants
Very low
Adverse effects · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
1 finding from 1 review
Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events
1 study · 220 participants
Very low
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
It is very uncertain whether 1000 mg champignon extract changes patient-reported visual analogue scale (VAS) score (scale 0 to 100) compared with placebo (very low certainty).
1 finding from 1 review
VSC: third component · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Chlorine dioxide mouthrinse (with tongue scraping) showed no clear difference in VSC: third component compared with chlorhexidine mouthwash (with tongue scraping); GRADE not reported.
1 finding from 1 review
OLT score and patient self-assessment (BANA test) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
Gingival pocketing (long term) · Adults (mean age 30.9 years), level of ID unclear; setting day centre
Scheduled dental recall intervals (1-, 3- or 6-monthly; oral hygiene… may leads to lower gingival pocketing (long term) compared with usual care (no specific treatment) (low certainty).
1 finding from 1 review
Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Day 2012 used a formal methodology to identify and report adverse effects, with none identified.
1 study · 22 participants
GRADE not reported
Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
VSC: methyl mercaptan · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Chlorine dioxide mouthrinse (with tongue scraping) showed no clear difference in VSC: methyl mercaptan compared with chlorhexidine mouthwash (with tongue scraping); GRADE not reported.
1 finding from 1 review
Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Sodium bicarbonate toothpaste showed no clear difference in volatile sulphur compounds (VSC) compared with control toothpaste (without sodium bicarbonate); GRADE not reported.
1 finding from 1 review
Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Scaling and root planing (SRP) plus glycine powder air polishing showed no clear difference in volatile sulphur compounds (VSC), halimeter compared with scaling and root planing (SRP) alone; GRADE not reported.
1 finding from 1 review
Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Essential oil mouthwash showed no clear difference in volatile sulphur compounds (VSC), halimeter compared with placebo mouthwash; GRADE not reported.
2 findings from 1 review
Interventions for managing halitosis 2019 · Cochrane All outcomes2 weeks
MD -5.13 [-32.94, 22.68]
1 study · 45 participants
GRADE not reported
Garcia 2014 (2-arm RCT) compared essential oil mouthwash versus placebo mouthwash (VSC by halimeter). We could not include the results in the meta-analysis because of the missing SD and P value.
1 study
GRADE not reported
Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
Cetylpyridinium chloride mouthwash led to lower volatile sulphur compounds (VSC), halimeter compared with placebo mouthwash; GRADE not reported.
1 finding from 1 review
Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
It is very uncertain whether hinokitiol gel changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with placebo gel (very low certainty).
1 finding from 1 review
Patient's family member-reported VAS score (scale 0 to 100) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1000 mg champignon extract showed no clear difference in patient's family member-reported VAS score (scale 0 to 100) compared with placebo; GRADE not reported.
1 finding from 1 review
Incidence of ORN · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
It is very uncertain whether hyperbaric oxygen therapy (HBO) following extractions changes incidence of ORN compared with perioperative antibiotic prophylaxis (penicillin G) following… (very low certainty).
1 finding from 1 review