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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

581 questions in 23 reviews · Implants and prosthodontics

current versions
No studies 87 · 15%Ungraded 388 · 66.8%Very low 88 · 15.1%Low 10 · 1.7%Moderate 8 · 1.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Rotary instruments to open the lateral sinus window vs Piezosurgery to open the lateral sinus window
Complications at donor site · Patients undergoing lateral-window maxillary sinus lift · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Rickert 2013 (N = 36): no complications at donor site.1 study · 36 participantsUngraded
Dual mini-screw implant vs Single mini-screw implant
Residual overjet at the end of treatment · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
No studies reported on residual overjet at the end of treatment for the comparison of two types of surgical anchorage0 studiesNo studies
Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation
Patient preference · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the… · 4 to 5 months after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Felice 2009a: all patients expressed no preference (biased by design). Esposito 2012: five months after loading, 15 patients preferred short implants whereas 5 described both procedures as equally acceptable.2 studiesUngraded
ITI SLA standard (regular neck) implants vs ITI SLActive implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 5.00 [0.26, 98.00]1 study · 40 participantsUngraded
Resorbable barrier (membrane) to seal the lateral window vs No membrane to seal the lateral window
Prosthesis failure · Patients undergoing lateral-window maxillary sinus lift · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 2.63 [0.75, 9.14]1 study · 104 participantsUngraded
Ankylos Plus (Dentsply) implants vs Seven (Sweden & Martina) implants
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD 0.03 [-0.29, 0.35]1 study · 48 participantsUngraded
Osteotomes with mallet (Summers' technique) vs Rotary instruments (Cosci technique)
Prosthesis failure · Patients undergoing crestal maxillary sinus lift · 3 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Checchi 2010 (split-mouth, N = 12): no prosthetic failures in either group.1 study · 12 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Patient acceptability · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
Reported narratively in 1 study (Feldmann 2007): limitations in daily life and jaw function were low to moderate throughout the trial with no differences between anchorage groups; impact on mood and appearance peaked…1 study · 113 participantsUngraded
Southern regular implants vs Southern wide implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 3.25 [0.15, 72.36]1 study · 23 participantsUngraded
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)
Bone gain · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 18 months after augmentation
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
MD -0.10 [-0.47, 0.27]1 study · 39 participantsUngraded
Turned (smoother) implant surfaces vs Roughened implant surfaces
Early implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · before prosthetic loading, turned vs roughened surfaces
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 2.79 [0.87, 8.90]7 studies · 404 participantsLow
Astra TiO2-blasted titanium screws vs Branemark turned titanium screws
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 5 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 0.25 [0.03, 2.12]1 study · 66 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Adverse events · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
This outcome was unreported in all included studies0 studiesNo studies
Bone graft with platelet-rich plasma (PRP) vs Bone graft without PRP
Complications · Patients with insufficient bone below the maxillary sinus requiring dental implants · 2 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Raghoebar 2005: 1 complication in the non-PRP arm, OR 0.27 (0.01 to 8.46), P = 0.46; Torres 2009 (PRP only = 3, no-PRP only = 2), OR 1.49 (0.15 to 15.07), P = 1.00. No statistically significant difference.2 studies · 62 participantsUngraded
One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long
Complications · Patients with 3 to 6 mm of residual bone height at the sinus floor · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.21 [0.02, 2.08]1 study · 40 participantsUngraded
SPI Element sand-blasted acid-etched standard implants vs SPI Element SurfLink-modified implants
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD 0.27 [-0.01, 0.55]1 study · 42 participantsUngraded
Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation
Complications (at treated sites) · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the… · median 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Peto OR 4.77 [1.79, 12.71]4 studies · 137 participantsLow
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Mesiodistal movement of the upper first permanent molar · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to… · End of anchorage reinforcement / space closure
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
MD -1.68 [-2.27, -1.09]7 studies · 308 participantsModerate
ITI SLA titanium screws vs Southern blasted/etched titanium screws
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 10 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD -0.02 [-0.18, 0.14]1 study · 24 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Success or failure of the anchorage device · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
Reported in 5 studies but not pooled due to variability in the definition of success and incomplete reporting. Success rates: mini-implants 71.43% (10/14) (Basha 2010); Orthosystem mid-palatal implant 91.30% (21/23) vs…5 studiesUngraded
NobelActive external connection implants vs NobelReplace implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 3 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 0.67 [0.17, 2.67]1 study · 106 participantsUngraded
Branemark Mark IV TiUnite titanium screws vs Southern regular titanium screws
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 0.57 [0.20, 1.63]1 study · 38 participantsUngraded
ITI SLA titanium implants vs SwissPlus (Zimmer) cylindrical implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 5 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures at 5 years; risk ratio not estimable (Akoglu 2011)1 studyUngraded
One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long
Implant failure · Patients with 3 to 6 mm of residual bone height at the sinus floor · 5 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.30 [0.03, 3.15]1 study · 40 participantsUngraded
Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation
Augmentation procedure failure · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the… · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
One bilateral augmentation failure occurred in one trial only (Felice 2011).1 studyUngraded
Astra TiO2-blasted titanium screws vs Branemark turned titanium screws
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 5 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD -0.09 [-0.33, 0.15]1 study · 65 participantsUngraded
MegaGen EZ Plus blasted standard implants vs MegaGen EZ Plus calcium-incorporated (Xpeed) implants
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD 0.04 [-0.13, 0.21]1 study · 60 participantsUngraded
Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation
Implant failure · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the… · median 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Peto OR 0.44 [0.10, 1.99]4 studies · 137 participantsModerate
One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long
Partial graft loss · Patients with 3 to 6 mm of residual bone height at the sinus floor · 5 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.63 [0.09, 4.24]1 study · 40 participantsUngraded
Dual mini-screw implant vs Single mini-screw implant
Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
RR 1.01 [0.84, 1.22]1 study · 25 participantsUngraded
One-stage lateral sinus lift with monocortical autogenous bone blocks (iliac crest) vs Two-stage lateral sinus lift with autogenous particulate bone (iliac crest)
Implant failure · Patients with 2 to 7 mm of residual alveolar bone height in the edentulous maxillary sinus floor · 3 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 1.56 [0.42, 5.76]1 study · 40 participantsUngraded
Branemark Mark III turned titanium implants vs Branemark Mark III TiUnite oxidised implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures (Froberg 2006, Table 1); risk ratio not estimable1 study · 15 participantsUngraded
Branemark Mark IV turned titanium implants vs Branemark Mark IV TiUnite oxidised implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 0.33 [0.82, 7.32]1 study · 20 participantsUngraded
Branemark Mark IV turned titanium implants vs Branemark Mark IV TiUnite oxidised implants
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 to 3 years
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD 0.11 [-0.38, 0.60]1 study · 20 participantsUngraded
ITI SLActive titanium grade 4 implants vs ITI SLActive titanium-13zirconium (Roxolid) implants
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 2.00 [0.18, 21.66]1 study · 178 participantsUngraded
Osteotomes with mallet (Summers' technique) vs Rotary instruments (Cosci technique)
Patient preference · Patients undergoing crestal maxillary sinus lift · 5 months after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Five months after loading, 13 of 15 patients preferred the side treated with the Cosci (rotary) technique; binomial test P = 0.007 (significant). Basis for the review's low-quality-evidence statement that patients may…1 study · 15 participantsUngraded
Rotary instruments to open the lateral sinus window vs Piezosurgery to open the lateral sinus window
Prosthesis failure · Patients undergoing lateral-window maxillary sinus lift · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Rickert 2013 (split-mouth, N = 36): no prosthesis failures in either group.1 study · 36 participantsUngraded
Implantium microthreads at the coronal top vs Implantium microthreads 0.5 mm below the top
Implant failure · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
No failures; risk ratio not estimable (Song 2009)1 study · 20 participantsUngraded
Dual mini-screw implant vs Single mini-screw implant
Duration of space closure · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
MD -2.19 [-6.35, 1.97]1 study · 25 participantsUngraded
NobelActive internal connection implants vs NobelReplace implants
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD 0.30 [-0.17, 0.77]1 study · 97 participantsUngraded
Hand mallet (osteotomes) vs Electric mallet
Implant failure · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about… · before loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 1.00 [0.06, 16.56]1 study · 80 participantsUngraded
One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long
Prosthesis failure · Patients with 3 to 6 mm of residual bone height at the sinus floor · 5 years after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.47 [0.04, 5.69]1 study · 40 participantsUngraded
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)
Prosthesis failure · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 0.63 [0.10, 4.22]1 study · 44 participantsUngraded
Turned (smoother) implant surfaces vs Roughened implant surfaces
Peri-implantitis · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 3 years, turned vs roughened surfaces
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
RR 0.80 [0.67, 0.96]4 studies · 144 participantsLow
NobelReplace Select Tapered implants vs NobelReplace Groovy implants
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD 0.29 [-0.06, 0.64]1 study · 62 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Residual overjet at the end of treatment · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
No studies reported on residual overjet at the end of treatment0 studiesNo studies
Rotary instruments to open the lateral sinus window vs Piezosurgery to open the lateral sinus window
Augmentation procedure failure · Patients undergoing lateral-window maxillary sinus lift · 1 year after loading
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
Rickert 2013 (N = 36): no augmentation procedure failures.1 study · 36 participantsUngraded
One-stage augmentation (implants placed simultaneously) vs Two-stage augmentation (delayed implant placement)
Implant failure · Patients requiring maxillary sinus augmentation · 1 year after loading (before loading)
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane
OR 3.48 [0.34, 35.61]1 study · 58 participantsUngraded
NobelActive external connection implants vs NobelReplace implants
Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed dental implants, functionally loaded and followed… · 1 year
Interventions for replacing missing teeth: different types of dental implants (2014) · Cochrane
MD 0.00 [-0.41, 0.41]1 study · 88 participantsUngraded
Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)
Patient perception: discomfort · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to…
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods (2014) · Cochrane
Reported narratively in 2 studies (Chesterfield 2007, 47 patients; Feldmann 2007, 113 patients) on a VAS 0-100; discomfort most severe the evening after surgery (Nobel-Biocare onplant median 33, IQR 0-96) and after…2 studies · 160 participantsUngraded