What do systematic reviews say?

Intervention not reported

The intervention may leads to lower paracetamol vs placebo (low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 0.75 [0.69, 0.82]
  6 studies · 655 participants
  Low

Intervention not reported

The intervention may leads to lower propacetamol vs placebo (low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 0.49 [0.35, 0.69]
  3 studies · 204 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes para/propacetamol vs NSAIDs (very low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 1.19 [0.87, 1.63]
  5 studies · 309 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes paracetamol vs NSAIDs (very low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 1.08 [0.59, 1.98]
  2 studies · 120 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes propacetamol vs NSAIDs (very low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 1.23 [0.86, 1.77]
  3 studies · 189 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes propacetamol vs opioids (very low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 1.83 [0.72, 4.64]
  2 studies · 139 participants
  Very low

Intervention not reported

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 777 participants
  Moderate

Intervention not reported

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 404 participants
  Low

Intervention not reported

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 373 participants
  Low

Intervention not reported

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 540 participants
  Very low

Intervention not reported

The intervention probably leads to higher propacetamol vs placebo see footnote1 (moderate certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 2.19 [1.74, 2.77]
  8 studies · 756 participants
  Moderate

Intervention not reported

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 160 participants
  Very low

Intervention not reported

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 380 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes para/propacetamol vs placebo (very low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 0.7 [0.57, 0.87]
  15 studies · 1414 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes paracetamol vs placebo (very low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 0.64 [0.51, 0.8]
  13 studies · 1037 participants
  Very low

Intervention not reported

The intervention showed no clear difference in propacetamol vs placebo (low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 1.62 [0.75, 3.48]
  3 studies · 377 participants
  Low

Intervention not reported

The intervention showed no clear difference in para/propacetamol vs NSAIDs see footnote1 (low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 1.01 [0.86, 1.18]
  5 studies · 353 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes paracetamol vs NSAIDs see footnote1 (very low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 0.9 [0.72, 1.13]
  2 studies · 130 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes propacetamol vs NSAIDs see footnote1 (very low certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 1.08 [0.86, 1.34]
  3 studies · 223 participants
  Very low

Intervention not reported

The intervention showed no clear difference in paracetamol vs propacetamol see footnote1 (moderate certainty).

• Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
  RR 0.98 [0.77, 1.24]
  3 studies · 361 participants
  Moderate