Findings

What do systematic reviews say?

87 questions · 88 findings · 12 reviews

No studies found 7 · 8%GRADE not reported 4 · 4.5%Very low 35 · 39.8%Low 21 · 23.9%Moderate 17 · 19.3%High 4 · 4.5%

Number of patients with at least 30% pain reduction · Patients with fibromyalgia

It is very uncertain whether the intervention changes number of patients with at least 30% pain reduction (very low certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors for fibromyalgia syndrome 2015 · Cochrane Headline outcomes only
RD 0.1 [0.01, 0.2]
6 studies · 343 participants
Very low

Number of patients with a clinically important global improvement · Patients with fibromyalgia

It is very uncertain whether the intervention changes number of patients with a clinically important global improvement (very low certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors for fibromyalgia syndrome 2015 · Cochrane Headline outcomes only
RD 0.14 [0.06, 0.23]
6 studies · 330 participants
Very low

Fatigue (lower scores mean less fatigue) · Patients with fibromyalgia

1 finding from 1 review

Selective serotonin reuptake inhibitors for fibromyalgia syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 192 participants
Very low

Sleep problems (lower scores mean less sleep problems) · Patients with fibromyalgia

1 finding from 1 review

Selective serotonin reuptake inhibitors for fibromyalgia syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 193 participants
Very low

Depression (lower scores mean less depression) · Patients with fibromyalgia

1 finding from 1 review

Selective serotonin reuptake inhibitors for fibromyalgia syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 244 participants
Very low

Discontinuation due to adverse events · Patients with fibromyalgia

It is very uncertain whether the intervention changes discontinuation due to adverse events (very low certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors for fibromyalgia syndrome 2015 · Cochrane Headline outcomes only
RD 0.04
5 studies · 284 participants
Very low

Serious adverse events · Patients with fibromyalgia

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors for fibromyalgia syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 168 participants
Very low