Number of participants reporting an adverse event · sleep disturbances in dementia
Orexin antagonists showed no clear difference in reporting ≥ 1 adverse event compared with placebo (moderate certainty).
1 finding from 1 review
Cognitive function · sleep disturbances in dementia
1 finding from 1 review
Consolidated sleep time · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change from baseline in carer distress · sleep disturbances in dementia
1 finding from 1 review
Number of nocturnal awakenings · sleep disturbances in dementia
1 finding from 1 review
Number of participants reporting an adverse event · sleep disturbances in dementia
Melatonin showed no clear difference in reporting ≥ 1 adverse event compared with placebo (low certainty).
1 finding from 1 review
Cognitive function · sleep disturbances in dementia
1 finding from 1 review
Quality of life · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Carer burden · sleep disturbances in dementia
1 finding from 1 review
Total nocturnal sleep time (minutes) · sleep disturbances in dementia
1 finding from 1 review
Consolidated nocturnal sleep time · sleep disturbances in dementia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of dementia · cognitively healthy people in late life
Aspirin showed no clear difference in incidence of dementia compared with placebo (high certainty).
1 finding from 1 review
All‐cause mortality · cognitively healthy people in late life
Other NSAIDs showed no clear difference in mortality compared with placebo (moderate certainty).
1 finding from 1 review
Incidence of mild cognitive impairment · cognitively healthy people in late life
Other NSAIDs showed no clear difference in incidence of mild cognitive impairment compared with placebo (low certainty).
1 finding from 1 review
Activities of daily living · cognitively healthy people in late life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · cognitively healthy people in late life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of dementia · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Gastrointestinal adverse events · older people with age‐related memory loss
NSAIDs (celecoxib) may leads to higher adverse events – gastrointestinal compared with placebo (low certainty).
1 finding from 1 review
All‐cause mortality · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found