Findings

What do systematic reviews say?

91 questions · 91 findings · 4 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 27 · 29.7%GRADE not reported 0 · 0%Very low 40 · 44%Low 19 · 20.9%Moderate 3 · 3.3%High 2 · 2.2%

Summary of findings ‐ PEP vs airway clearance techniques

Direct measures of mucus clearance: radioisotope retention · adults and children with cystic fibrosis

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
31 participants
Low

Summary of findings ‐ PEP vs airway clearance techniques

Exercise capacity · adults and children with cystic fibrosis

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Low

Summary of findings ‐ PEP vs airway clearance techniques

Well being: Short Form ‐36 · adults and children with cystic fibrosis

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Low

Summary of findings ‐ PEP vs airway clearance techniques

LCI · adults and children with cystic fibrosis

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
6 participants
Very low

Summary of findings ‐ PEP vs airway clearance techniques

Adverse events · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ PEP vs PDPV

Exercise capacity · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 66 participants
Low

Summary of findings ‐ PEP vs PDPV

Well being: QWB scale · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 66 participants
Low

Summary of findings ‐ PEP vs PDPV

LCI · adults and children with CF

The review found no eligible studies for this question.

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ PEP vs PDPV

Adverse events · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 66 participants
Low

Summary of findings ‐ PEP vs oscillating PEP

FEV1 % predicted: absolute change from baseline · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 217 participants
Moderate

Summary of findings ‐ PEP vs oscillating PEP

Number of respiratory exacerbations: requiring either IV antibiotics or hospitalisation · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 112 participants
Moderate