Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

336 questions · 354 findings · 32 reviews · Haematology

No studies found 71 · 20.1%GRADE not reported 33 · 9.3%Very low 70 · 19.8%Low 82 · 23.2%Moderate 75 · 21.2%High 23 · 6.5%

Intervention not reported

All‐cause mortality at 31 to 100 days · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

It is very uncertain whether the intervention changes all‐cause mortality at 31 to 100 days (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants with any bleeding ‐ not reported · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Length of hospital admission ‐ not reported · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Hospital readmission rate ‐ not reported · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Number of participants with any bleeding (0 to 3 months) · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The intervention showed no clear difference in number of participants with any bleeding (0 to 3 months) (low certainty).

1 finding from 1 review

Intervention not reported

Number of participants with clinically significant bleeding (0 to 3 months) · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The intervention showed no clear difference in number of participants with clinically significant bleeding (0 to 3… (low certainty).

1 finding from 1 review

Intervention not reported

Serious infections (0 to 3 months) · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The intervention showed no clear difference in serious infections (0 to 3 months) (low certainty).

1 finding from 1 review

Intervention not reported

Hospital readmission (0 to 3 months) · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The intervention showed no clear difference in hospital readmission (0 to 3 months) (low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Antithrombin concentrates vs no antithrombin concentrates

Death Analysis 1.1 · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

It is very uncertain whether summary of Findings Table ‐ Antithrombin concentrates changes all‐cause mortality ‐ Intention‐to‐treat analysis compared with no antithrombin concentrates (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

Adverse events: clinically relevant non‐major bleeding / heparin‐induced thrombocytopenia ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review