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Evidence found and GRADE certainty

88 questions · 89 findings · 14 reviews · Skin

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No studies found 40 · 44.9%GRADE not reported 4 · 4.5%Very low 17 · 19.1%Low 20 · 22.5%Moderate 7 · 7.9%High 1 · 1.1%

Fractional laser vs combined chemical peeling plus needling

Participant‐reported scar improvement (long‐term) · people with acne scars

It is very uncertain whether fractional laser changes participant‐reported scar improvement (long‐term) N of participants… compared with combined chemical peeling plus needling (very low certainty).

1 finding from 1 review

Chemical peeling vs combined chemical peeling plus any active intervention

Participant‐reported scar improvement (long‐term) · people with acne scars

It is very uncertain whether chemical peeling changes participant‐reported scar improvement (long‐term) N of participants… compared with combined chemical peeling plus any active intervention (very low certainty).

1 finding from 1 review

Chemical peeling vs needling

Participant‐reported scar improvement (long‐term) · people with acne scars

The review found no eligible studies for this question.

1 finding from 1 review

Fractional laser vs radiofrequency

Participant‐reported scar improvement (long‐term) · people with acne scars

The review found no eligible studies for this question.

1 finding from 1 review

Ketoconazole vs ciclopirox

Failure to achieve complete resolution (long term) ‐ Face only Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole showed no clear difference in failure to achieve complete resolution (long term) ‐ Face only… compared with ciclopirox (low certainty).

1 finding from 1 review