Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

119 questions · 122 findings · 18 reviews · Common Mental Disorders

No studies found 29 · 23.8%GRADE not reported 12 · 9.8%Very low 39 · 32%Low 28 · 23%Moderate 14 · 11.5%High 0 · 0%

Discontinuation with high‐intensity psychological interventions vs continuation

Risk of relapse (as defined by study authors) (HR) · participants with long‐term antidepressants for depressive disorders

Discontinuation with high‐intensity psychological interventions showed no clear difference in risk of relapse (as defined by study authors) (HR) compared with continuation (low certainty).

1 finding from 1 review

Abrupt discontinuation vs continuation of long‐term antidepressants

Relapse · participants with depressive or anxiety disorders

It is very uncertain whether abrupt discontinuation changes relapse (as defined by study authors) (HR) compared with continuation of long‐term antidepressants (very low certainty).

1 finding from 1 review

Abrupt discontinuation vs continuation of long‐term antidepressants

Adverse events · participants with depressive or anxiety disorders

It is very uncertain whether abrupt discontinuation changes adverse events compared with continuation of long‐term antidepressants (very low certainty).

1 finding from 1 review