Findings

What do systematic reviews say?

82 questions · 83 findings · 15 reviews · Neuromuscular

No studies found 11 · 13.3%GRADE not reported 3 · 3.6%Very low 16 · 19.3%Low 20 · 24.1%Moderate 12 · 14.5%High 21 · 25.3%

Adverse event: asthenia · patients with ALS/MND

The intervention leads to higher adverse event: asthenia (high certainty).

1 finding from 1 review

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) 2012 · Cochrane Headline outcomes only
RR 1.5 [1.07, 2.12]
3 studies · 801 participants
High

Adverse event: 3‐fold increase in alanine transferase · patients with ALS/MND

The intervention leads to higher adverse event: 3‐fold increase in alanine transferase (high certainty).

1 finding from 1 review

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) 2012 · Cochrane Headline outcomes only
RR 2.62 [1.59, 4.31]
3 studies · 801 participants
High