Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

89 questions · 91 findings · 6 reviews · Neuromuscular

No studies found 26 · 28.6%GRADE not reported 8 · 8.8%Very low 23 · 25.3%Low 14 · 15.4%Moderate 17 · 18.7%High 3 · 3.3%

Interferon beta‐1a vs placebo

Participants who completed the study and did not restart IVIg therapy after IVIg withdrawal · people with CIDP

Interferon beta‐1a showed no clear difference in participants who completed the study and did not restart IVIg… compared with placebo (moderate certainty).

1 finding from 1 review

IVIg vs PE

Number improved by 1 or more disability grades after 4 weeks · patients with Guillain‐Barré syndrome

IVIg showed no clear difference in number improved by 1 or more disability grades after 4 weeks compared with PE (moderate certainty).

1 finding from 1 review

IVIg vs PE

Dead or disabled after 12 months (48 weeks) · patients with Guillain‐Barré syndrome

IVIg showed no clear difference in dead or disabled after 12 months (48 weeks) compared with PE (low certainty).

1 finding from 1 review

IVIg vs PE

Relapse or treatment‐related fluctuation · patients with Guillain‐Barré syndrome

IVIg showed no clear difference in relapse or treatment‐related fluctuation compared with PE (low certainty).

1 finding from 1 review

IVIg vs PE

Patients in whom treatment was discontinued · patients with Guillain‐Barré syndrome

IVIg leads to lower participants in whom treatment was discontinued compared with PE (high certainty).

1 finding from 1 review

IVIg vs PE

Number of patients with adverse events attributed to treatment · patients with Guillain‐Barré syndrome

IVIg showed no clear difference in number of participants with adverse events attributed to treatment compared with PE (moderate certainty).

1 finding from 1 review