Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

173 questions · 174 findings · 12 reviews · Headline outcomes only

No studies found 34 · 19.5%GRADE not reported 26 · 14.9%Very low 34 · 19.5%Low 40 · 23%Moderate 25 · 14.4%High 15 · 8.6%

Intervention not reported

Intervention Total studies: 4* Total participants: 379 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

The intervention showed no clear difference in intervention Total studies: 4* Total participants: 379; GRADE not reported.

1 finding from 1 review

Intervention not reported

IPC –not daily drainage (2 RCTs, 160 participants) VAS scores at 42 days and 180 days · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review

Intervention not reported

Total studies: 31* Total participants: 2816 No. interventions in network: 15 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

The intervention led to lower total studies: 31* Total participants: 2816 No. interventions in…; GRADE not reported.

1 finding from 1 review

Intervention not reported

Intervention Total studies: 9 Total participants: 883 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

The intervention led to lower intervention Total studies: 9 Total participants: 883; GRADE not reported.

1 finding from 1 review