Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

165 questions · 165 findings · 18 reviews

No studies found 65 · 39.4%GRADE not reported 6 · 3.6%Very low 25 · 15.2%Low 31 · 18.8%Moderate 33 · 20%High 5 · 3%

Paracervical vs intravenous diazepam/pethidine analgesia

Providers' satisfaction with the procedure · women with persistent or prolonged retention of placenta

It is very uncertain whether paracervical block changes providers' satisfaction with the procedure compared with intravenous diazepam/pethidine analgesia (very low certainty).

1 finding from 1 review

Paracervical vs intravenous diazepam/pethidine analgesia

Women's satisfaction with the procedure · women with persistent or prolonged retention of placenta

It is very uncertain whether paracervical block changes women's satisfaction with the procedure compared with intravenous diazepam/pethidine analgesia (very low certainty).

1 finding from 1 review

Baclofen vs diazepam

AW seizures · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

AW delirium · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

Global improvement · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

Craving · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

AEs · people with alcohol withdrawal

It is very uncertain whether baclofen changes AEs compared with diazepam (very low certainty).

1 finding from 1 review

Baclofen vs diazepam

Severe AEs · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

Leaving the study early · people with alcohol withdrawal

It is very uncertain whether baclofen changes dropouts compared with diazepam (very low certainty).

1 finding from 1 review

Baclofen vs diazepam

Dropouts due to adverse events · people with alcohol withdrawal

It is very uncertain whether baclofen changes dropouts due to AEs compared with diazepam (very low certainty).

1 finding from 1 review

Summary of findings ‐ Intravenous lorazepam vs intravenous diazepam/intravenous phenytoin combination

Seizure cessation: within 10 minutes · Children with acute tonic‐clonic seizures

Summary of findings ‐ Intravenous lorazepam showed no clear difference in seizure cessation: within 10 minutes compared with intravenous diazepam/intravenous phenytoin combination (moderate certainty).

1 finding from 1 review

Summary of findings ‐ Intravenous lorazepam vs intravenous diazepam/intravenous phenytoin combination

Incidence of respiratory depression · Children with acute tonic‐clonic seizures

Summary of findings ‐ Intravenous lorazepam showed no clear difference in incidence of respiratory depression compared with intravenous diazepam/intravenous phenytoin combination (moderate certainty).

1 finding from 1 review

Summary of findings ‐ Intravenous lorazepam vs intravenous diazepam/intravenous phenytoin combination

Additional drugs required to stop the seizure · Children with acute tonic‐clonic seizures

Summary of findings ‐ Intravenous lorazepam showed no clear difference in additional drugs required to stop the seizure compared with intravenous diazepam/intravenous phenytoin combination (moderate certainty).

1 finding from 1 review

Summary of findings ‐ Buccal midazolam vs rectal diazepam

Seizure cessation: within 5 minutes to 1 hour · Children with acute tonic‐clonic seizures

It is very uncertain whether summary of findings ‐ Buccal midazolam changes seizure cessation: within 5 minutes to 1 hour compared with rectal diazepam (very low certainty).

1 finding from 1 review