Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

170 questions · 183 findings · 10 reviews · Gut

No studies found 1 · 0.5%GRADE not reported 3 · 1.6%Very low 50 · 27.3%Low 37 · 20.2%Moderate 60 · 32.8%High 32 · 17.5%

Intervention not reported

the toxic and side effects in digestive system after chemotherapy (no special data in trial of Zhang 2006) · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy… (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects in digestive system after chemotherapy · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects of leukopenia after chemotherapy · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects of leukopenia after chemotherapy(no special data in trial of Zhang 2006) · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy(no… (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects in digestive system after chemotherapy · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects of leukopenia after chemotherapy(no special data in trial of Jia 2003, Zhang 2009) · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy(no… (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects in digestive system after chemotherapy(no special data in trial of Fu 2011, Liu 2009a, Zhang 2010) · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy(no… (very low certainty).

1 finding from 1 review

Intervention not reported

the toxic and side effects of leukopenia after chemotherapy · patients with induction of remission in advanced or late gastric cancer

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy (very low certainty).

1 finding from 1 review

Chemmotherapy combined with biological therapy vs chemotherapy alone

Overall survival · advanced gastric and oesophago‐gastric junction adenocarcinoma

Chemmotherapy combined with biological therapy showed no clear difference in overall survival compared with chemotherapy (moderate certainty).

1 finding from 1 review

Chemmotherapy combined with biological therapy vs chemotherapy alone

Progression‐free survival · advanced gastric and oesophago‐gastric junction adenocarcinoma

It is very uncertain whether chemmotherapy combined with biological therapy changes progression‐free survival compared with chemotherapy (very low certainty).

1 finding from 1 review

Chemmotherapy combined with biological therapy vs chemotherapy alone

Serious adverse events · advanced gastric and oesophago‐gastric junction adenocarcinoma

It is very uncertain whether chemmotherapy combined with biological therapy changes serious adverse events compared with chemotherapy (very low certainty).

1 finding from 1 review

Chemmotherapy combined with biological therapy vs chemotherapy alone

Tumour response · advanced gastric and oesophago‐gastric junction adenocarcinoma

It is very uncertain whether chemmotherapy combined with biological therapy changes tumour response rate compared with chemotherapy (very low certainty).

1 finding from 1 review

Chemmotherapy combined with biological therapy vs chemotherapy alone

Any adverse events · advanced gastric and oesophago‐gastric junction adenocarcinoma

Chemmotherapy combined with biological therapy showed no clear difference in any adverse events compared with chemotherapy (moderate certainty).

1 finding from 1 review