Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

131 questions · 139 findings · 18 reviews

No studies found 35 · 25.2%GRADE not reported 17 · 12.2%Very low 32 · 23%Low 19 · 13.7%Moderate 31 · 22.3%High 5 · 3.6%

Oral azithromycin vs control

Ocular chlamydia trachomatis infection · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Oral azithromycin vs control

Antibiotic resistance · people (any age) with active trachoma

Oral azithromycin led to lower antibiotic resistance Proportion of samples showing evidence of… compared with control; GRADE not reported.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    4 studies · 1354 participants
    GRADE not reported

Oral azithromycin vs control

Active trachoma · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Azithromycin + SRP vs SRP

Probing pocket depth · Adults with periodontitis (chronic and aggressive)

Azithromycin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.

3 findings from 1 review

Azithromycin + SRP vs SRP

Percentage of closed pockets · Adults with periodontitis (chronic and aggressive)

Azithromycin + SRP showed no clear difference in percentage of closed pockets compared with SRP; GRADE not reported.

2 findings from 1 review

Azithromycin + SRP vs SRP

Percentage of bleeding on probing (BOP) · Adults with periodontitis (chronic and aggressive)

Azithromycin + SRP led to lower percentage of bleeding on probing (BOP) compared with SRP; GRADE not reported.

3 findings from 1 review

Azithromycin + SRP vs SRP

Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)

It is very uncertain whether azithromycin + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).

3 findings from 1 review

Azithromycin + SRP vs SRP

Adverse events · Adults with periodontitis (chronic and aggressive)

It is very uncertain whether azithromycin + SRP changes adverse events compared with SRP (very low certainty).

1 finding from 1 review