Adverse effects · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…
It is very uncertain whether neurohormones changes adverse effects compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects sufficient to stop treatment · Children aged 6 to 18 years with ASD
Memantine showed no clear difference in adverse effects Assessed by the study authors as those that were… compared with placebo (low certainty).
1 finding from 1 review
Language · Children aged 6 to 18 years with ASD
1 finding from 1 review
Memory (specific cognitive function) · Children aged 6 to 18 years with ASD
1 finding from 1 review
Adaptive behaviour · Children aged 6 to 18 years with ASD
1 finding from 1 review
Hyperactivity · Children aged 6 to 18 years with ASD
1 finding from 1 review
Irritability · Children aged 6 to 18 years with ASD
1 finding from 1 review
Impaired social interaction · children aged 5 to 11 years with ASD
1 finding from 1 review
Social communication impairment · children aged 5 to 11 years with ASD
1 finding from 1 review
Stereotyped patterns of behaviour and interests · children aged 5 to 11 years with ASD
1 finding from 1 review
Total adverse events · children aged 5 to 11 years with ASD
D‐cycloserine showed no clear difference in total adverse events compared with placebo (low certainty).
1 finding from 1 review
Non‐core symptoms of ASD · children aged 5 to 11 years with ASD
D‐cycloserine showed no clear difference in non‐core symptoms of ASD compared with placebo (low certainty).
1 finding from 1 review
Tolerability · children aged 5 to 11 years with ASD
D‐cycloserine showed no clear difference in tolerability compared with placebo (low certainty).
1 finding from 1 review
Inattention Measured using SNAP‐IV inattention subscale (range 0 to 27) · Children aged 6 to 18 years with ASD
2 findings from 1 review
Impulsivity · Children aged 6 to 18 years with ASD
2 findings from 1 review
Hyperactivity · Children aged 6 to 18 years with ASD
2 findings from 1 review
Impaired social interaction · Children aged 6 to 18 years with ASD
2 findings from 1 review
Impaired communication · Children aged 6 to 18 years with ASD
2 findings from 1 review
Stereotypical behaviours · Children aged 6 to 18 years with ASD
2 findings from 1 review
Overall ASD · Children aged 6 to 18 years with ASD
2 findings from 1 review