Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

109 questions · 112 findings · 3 reviews · Kidney and Transplant

No studies found 26 · 23.2%GRADE not reported 1 · 0.9%Very low 10 · 8.9%Low 50 · 44.6%Moderate 25 · 22.3%High 0 · 0%

Angiotensin receptor blockers (ARBs) vs placebo or no treatment

Death (all causes) · people with diabetes and kidney disease

Angiotensin receptor blockers showed no clear difference in all‐cause death Median compared with placebo or no treatment (low certainty).

1 finding from 1 review

Angiotensin receptor blockers (ARBs) vs placebo or no treatment

Cardiovascular mortality · people with diabetes and kidney disease

Angiotensin receptor blockers showed no clear difference in cardiovascular death Median compared with placebo or no treatment (low certainty).

1 finding from 1 review

Angiotensin receptor blockers (ARBs) vs placebo

Number of participants reporting an adverse event · adults with early (stage 1 to 3) non‐diabetic CKD

It is very uncertain whether angiotensin receptor blockers changes adverse events (number reporting an adverse event) compared with placebo (very low certainty).

1 finding from 1 review