Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,388 questions · 1,444 findings · 167 reviews

No studies found 336 · 23.3%GRADE not reported 67 · 4.6%Very low 419 · 29%Low 395 · 27.4%Moderate 188 · 13%High 39 · 2.7%

Corticosteroids vs placebo

Endoscopic improvement (dichotomous) · active EoE patients

Corticosteroids showed no clear difference in endoscopic improvement (dichotomous) compared with placebo (low certainty).

1 finding from 1 review

Esomeprazole vs fluticasone

Histological improvement (dichotomous) · active EoE patients

It is very uncertain whether esomeprazole changes histological improvement at 8 weeks (dichotomous) compared with fluticasone (very low certainty).

1 finding from 1 review

Esomeprazole vs fluticasone

Withdrawals due to adverse events · active EoE patients

It is very uncertain whether esomeprazole changes withdrawals due to adverse events at 8 weeks compared with fluticasone (very low certainty).

1 finding from 1 review