Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,378 questions · 2,146 findings · 145 reviews

No studies found 167 · 7.8%GRADE not reported 1,674 · 78%Very low 148 · 6.9%Low 113 · 5.3%Moderate 40 · 1.9%High 4 · 0.2%

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs placebo or no treatment

Fluorosis (mandibular teeth) at 5 years · Pregnant women (for preventing dental caries in the primary teeth of their children)

It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes fluorosis (mandibular teeth) at 5 years compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs placebo or no treatment

Decayed primary surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)

Fluoride supplementation (tablets, drops, lozenges or chewing gum) showed no clear difference in decayed primary surfaces at 3 years compared with placebo or no treatment; GRADE not reported.

2 findings from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Restoration failure (permanent, immature teeth) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)

ART using glass ionomer cement (GIC) led to higher restoration failure (permanent, immature teeth) compared with conventional treatment using amalgam; GRADE not reported.

1 finding from 1 review

ART using composite resin vs Conventional treatment using composite resin

Restoration failure (primary dentition) · Children with carious primary teeth

It is very uncertain whether ART using composite resin changes restoration failure (primary dentition) compared with conventional treatment using composite resin (very low certainty).

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Pain (permanent, immature teeth) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)

ART using glass ionomer cement (GIC) led to lower pain (permanent, immature teeth) compared with conventional treatment using amalgam; GRADE not reported.

1 finding from 1 review

High-viscosity glass-ionomer ART restorations vs Conventional treatment using H-GIC (rotary instruments)

Restoration failure (permanent dentition) · People with dental caries in primary teeth (mainly children)

The review found no eligible studies for this question.

1 finding from 1 review

High-viscosity glass-ionomer ART restorations vs Conventional treatment using H-GIC (rotary instruments)

Restoration failure (primary dentition) · People with dental caries in primary teeth (mainly children)

ART using high-viscosity glass ionomer cement (H-GIC), hand… may leads to higher restoration failure (primary dentition) compared with conventional treatment using H-GIC (rotary instruments) (low certainty).

1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs placebo or no treatment

Decayed or filled primary tooth surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)

It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes decayed or filled primary tooth surfaces at 3 years compared with placebo or no treatment (very low certainty).

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Participant experience (co-operation during procedure) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)
1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs placebo or no treatment

Decayed or filled primary tooth surfaces at 5 years · Pregnant women (for preventing dental caries in the primary teeth of their children)

It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes decayed or filled primary tooth surfaces at 5 years compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Dental caries: dmfs increment (primary teeth) · Children and adolescents aged 16 years or less

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Proportion developing new caries · Children and adolescents aged 16 years or less

Fluoride mouthrinse (any fluoride agent, concentration, volume,… showed no clear difference in proportion of children developing one or more new caries compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Secondary caries · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…

The review found no eligible studies for this question.

1 finding from 1 review