Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,653 questions in 194 reviews · Gynaecology and Fertility

current versions
No studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Conical blunt‐tipped trocar vs cutting trocar
Postoperative pain5 · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 42 participantsVery low
Radially expanding trocar vs conical blunt‐tipped trocar
Visceral injury · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Radially expanding trocar vs conical blunt‐tipped trocar
Vascular injury · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Radially expanding trocar vs conical blunt‐tipped trocar
Trocar site herniation · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Single‐bladed trocar vs pyramidal‐bladed trocar
Visceral injury · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Single‐bladed trocar vs pyramidal‐bladed trocar
Vascular injury · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Single‐bladed trocar vs pyramidal‐bladed trocar
Trocar site herniation · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Radially expanding trocars vs cutting trocars
Vascular injury · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
OR 0.14 [0, 7.16]4 studies · 473 participantsVery low
Radially expanding trocars vs cutting trocars
Trocar site herniation · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted4 studies · 463 participantsVery low
Radially expanding trocars vs cutting trocars
Trocar site bleeding · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
OR 0.28 [0.14, 0.54]5 studies · 553 participantsVery low
Radially expanding trocars vs cutting trocars
Trocar site haematoma5 · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted2 studies · 238 participantsVery low
Radially expanding trocars vs cutting trocars
Postoperative pain6 · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted4 studies · 306 participantsUngraded
Conical blunt‐tipped trocar vs cutting trocar
Visceral injury · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 42 participantsVery low
Conical blunt‐tipped trocar vs cutting trocar
Vascular injury · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
no estimate extracted1 study · 42 participantsVery low
Conical blunt‐tipped trocar vs cutting trocar
Trocar site bleeding · people undergoing laparoscopy
Trocar types in laparoscopy (2015) · Cochrane
OR 0.13 [0.01, 2.12]1 study · 30 participantsVery low
GnRH‐a + medroxyprogesterone acetate vs GnRH‐a ± placebo
Quality of life · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + tibolone vs GnRH‐a ± placebo
Uterine bleeding · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + tibolone vs GnRH‐a ± placebo
Severity of vasomotor symptoms (SMD) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted4 studies · 268 participantsUngraded
GnRH‐a + tibolone vs GnRH‐a ± placebo
Rate of vasomotor symptoms ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
RR 0.38 [0.14, 1.02]1 study · 20 participantsLow
GnRH‐a + raloxifene vs GnRH‐a ± placebo
Quality of life (SMD) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 74 participantsLow
GnRH‐a + raloxifene vs GnRH‐a ± placebo
Bone density (SMD) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 91 participantsLow
GnRH‐a + raloxifene vs GnRH‐a ± placebo
Uterine size (cm3) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 91 participantsLow
GnRH‐a + raloxifene vs GnRH‐a ± placebo
Uterine bleeding (VAS) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 91 participantsLow
GnRH‐a + raloxifene vs GnRH‐a ± placebo
Severity of vasomotor symptoms (no. of hot flushes per day) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 91 participantsLow
GnRH‐a + raloxifene vs GnRH‐a ± placebo
Rate of vasomotor symptoms · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + estriol vs GnRH‐a ± placebo
Quality of life · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + medroxyprogesterone acetate vs GnRH‐a ± placebo
Bone density (SMD) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 16 participantsLow
GnRH‐a + estriol vs GnRH‐a ± placebo
Bone density (SMD) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 12 participantsLow
GnRH‐a + estriol vs GnRH‐a ± placebo
Uterine Size · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + estriol vs GnRH‐a ± placebo
Uterine bleeding · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + estriol vs GnRH‐a ± placebo
Severity of vasomotor symptoms · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + estriol vs GnRH‐a ± placebo
Rate of vasomotor symptoms · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + ipriflavone vs GnRH‐a ± placebo
Quality of life · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + ipriflavone vs GnRH‐a ± placebo
Bone density (SMD) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 95 participantsLow
GnRH‐a + ipriflavone vs GnRH‐a ± placebo
Uterine size · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + ipriflavone vs GnRH‐a ± placebo
Uterine bleeding · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + ipriflavone vs GnRH‐a ± placebo
Severity of vasomotor symptoms · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + medroxyprogesterone acetate vs GnRH‐a ± placebo
Uterine size (cm3) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted2 studies · 32 participantsLow
GnRH‐a + ipriflavone vs GnRH‐a ± placebo
Rate of vasomotor symptoms ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
RR 0.67 [0.44, 1.02]1 study · 95 participantsLow
GnRH‐a + conjugated estrogens vs GnRH‐a ± placebo
Reduction in uterine size · women with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 27 participantsVery low
GnRH‐a + medroxyprogesterone acetate vs GnRH‐a ± placebo
Uterine bleeding · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + medroxyprogesterone acetate vs GnRH‐a ± placebo
Severity of vasomotor symptoms · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extractedNRNo studies
GnRH‐a + medroxyprogesterone acetate vs GnRH‐a ± placebo
Rate of vasomotor symptoms ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
RR 0.13 [0.02, 0.84]1 study · 16 participantsLow
GnRH‐a + tibolone vs GnRH‐a ± placebo
Quality of life (SMD) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted1 study · 110 participantsLow
GnRH‐a + tibolone vs GnRH‐a ± placebo
Bone density (SMD) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted3 studies · 160 participantsModerate
GnRH‐a + tibolone vs GnRH‐a ± placebo
Uterine size (cm3) ‐ · patients with uterine fibroids
Add‐back therapy with GnRH analogues for uterine fibroids (2015) · Cochrane
no estimate extracted6 studies · 365 participantsModerate
DHEA vs control (placebo or no treatment)
QoL, wellbeing (end scores) (sensitivity analysis) different scales for quality of life (QoL) · women in the peri‐ or postmenopausal phase
Dehydroepiandrosterone for women in the peri‐ or postmenopausal phase (2015) · Cochrane
no estimate extracted8 studies · 287 participantsModerate
DHEA vs HT
QoL, general wellbeing DHEA versus ET + P · Women in the peri‐ or postmenopausal phase
Dehydroepiandrosterone for women in the peri‐ or postmenopausal phase (2015) · Cochrane
no estimate extractedNRNo studies
DHEA vs HT
QoL, general wellbeing DHEA versus tibolone · Women in the peri‐ or postmenopausal phase
Dehydroepiandrosterone for women in the peri‐ or postmenopausal phase (2015) · Cochrane
no estimate extractedNRNo studies
DHEA vs HT
Acne DHEA versus ET · Women in the peri‐ or postmenopausal phase
Dehydroepiandrosterone for women in the peri‐ or postmenopausal phase (2015) · Cochrane
OR 17 [0.9, 320.37]1 study · 50 participantsVery low