Findings

What do systematic reviews say?

4,751 questions · 12,775 findings · 807 reviews · Headline outcomes only

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No studies found 3,413 · 26.7%GRADE not reported 709 · 5.5%Very low 3,483 · 27.3%Low 3,165 · 24.8%Moderate 1,628 · 12.7%High 377 · 3%

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Intervention not reported

Doxycycline (4 RCTs; 308 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 308 participants
Low

Intervention not reported

Placebo (2 RCTs; 118 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 118 participants
Low

Intervention not reported

Talc slurry (9 RCTs, 1320 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1320 participants
Low

Intervention not reported

Talc poudrage (4 RCTs, 886 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 886 participants
Very low

Intervention not reported

Bleomycin (13 RCTs, 724 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 724 participants
Low

Intervention not reported

IPC – not daily drainage (6 RCTs, 738 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 738 participants
Low

Intervention not reported

Talc slurry (19 RCTs, 907 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 907 participants
Moderate

Intervention not reported

Doxycycline (4 RCTs, 308 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 308 participants
Low

Intervention not reported

Placebo · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Intervention Total studies: 4* Total participants: 379 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

The intervention showed no clear difference in intervention Total studies: 4* Total participants: 379; GRADE not reported.

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 participants
GRADE not reported

Intervention not reported

Talc slurry (2 RCTs, 248 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 248 participants
Moderate

Intervention not reported

Talc poudrage (1 RCT, 184 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 184 participants
Moderate

Intervention not reported

Bleomycin (1 RCT, 35 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Very low

Intervention not reported

IPC –not daily drainage (2 RCTs, 160 participants) VAS scores at 42 days and 180 days · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 160 participants
Low

Intervention not reported

Doxycycline · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Placebo · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Talc poudrage (9 RCTs, 530 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 530 participants
Moderate

Intervention not reported

Talc slurry (13 RCTs, 1574 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1574 participants
Low

Intervention not reported

Talc poudrage (7 RCTs, 878 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 878 participants
Very low

Intervention not reported

Bleomycin (9 RCTs, 664 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 664 participants
Low