Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Therapeutic ultrasound vs placebo

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic low‐back pain

It is very uncertain whether therapeutic ultrasound changes pain intensity Scale: VAS (100‐point scale; higher scores mean… compared with placebo (very low certainty).

1 finding from 1 review

Therapeutic ultrasound vs placebo

At least 30% reduction in pain · adults with chronic low‐back pain

Therapeutic ultrasound showed no clear difference in pain intensity Scale: VAS (number of responders at 30% reduction of… compared with placebo (moderate certainty).

1 finding from 1 review

Therapeutic ultrasound plus exercise vs exercise

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic low‐back pain

It is very uncertain whether therapeutic ultrasound plus exercise changes pain intensity Scale: VAS (100‐point scale; higher scores mean… compared with exercise alone (very low certainty).

1 finding from 1 review

Intervention not reported

Cramp intensity (moderate or worse at 4 weeks) · pregnant women with leg cramps

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Cramp intensity (moderate or worse at 4 weeks) · for effects on cramps, people (other than pregnant women) with muscle cramps (largely older adults); for adverse events, all populations

The intervention showed no clear difference in cramp intensity (moderate or worse at 4 weeks) (moderate certainty).

1 finding from 1 review

Dopamine‐milrinone vs dopamine‐dobutamine

All‐cause short‐term mortality: at intensive care unit · adults with cardiogenic shock

It is very uncertain whether dopamine‐milrinone changes all‐cause short‐term mortality: at intensive care unit compared with dopamine‐dobutamine (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Composite outcome: symptoms of leg cramps (intensity and frequency) Complete recovery: no leg cramps after treatment · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes composite outcome: symptoms of leg cramps (intensity and frequency)… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Intensity of pain during treatment: mean total scale points The degree of pain was noted in the form, on a scale from 0 to 4 measured over 4 days and nights (0 = no pain, 1 = light pain, 2 = medium pain, 3=strong pain, 4=extreme pain) · treating leg cramps in pregnancy
1 finding from 1 review

Oral magnesium vs placebo/no treatment

At least 50% reduction in pain · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes intensity of pain: 50% reduction in pain score 100‐mm visual… compared with placebo/no treatment (very low certainty).

1 finding from 1 review