Findings

What do systematic reviews say?

1,368 questions · 1,413 findings · 89 reviews · Common Mental Disorders

Sort:Best matchNewest Highest certainty Download CSV

No studies found 232 · 16.4%GRADE not reported 82 · 5.8%Very low 395 · 28%Low 331 · 23.4%Moderate 341 · 24.1%High 32 · 2.3%

Paroxetine vs trazodone

SMD at endpoint · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 108 participants
Moderate

Paroxetine vs trazodone

Failure to complete ‐ any cause ‐ · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Paroxetine vs trazodone

Participants with at least some Side Effects · patients with depression

Paroxetine showed no clear difference in participants with at least some Side Effects compared with trazodone (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.68 [0.3, 1.55]
1 study · 108 participants
Moderate

Paroxetine vs venlafaxine

Failure to respond at endpoint (6‐12 weeks) · patients with depression

Paroxetine showed no clear difference in failure to respond at endpoint (6‐12 weeks) compared with venlafaxine (low certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.1 [0.58, 2.11]
4 studies · 747 participants
Low

Paroxetine vs venlafaxine

Failure to respond at 1‐4 weeks · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Paroxetine vs venlafaxine

Failure to respond at 16‐24 weeks · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Paroxetine vs agomelatine

Failure to complete ‐ any cause ‐ · patients with depression

Paroxetine showed no clear difference in failure to complete ‐ any cause ‐ compared with agomelatine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.99 [0.57, 1.71]
1 study · 284 participants
Moderate

Paroxetine vs venlafaxine

Failure to remit at endpoint · patients with depression

Paroxetine probably leads to higher failure to remit at endpoint compared with venlafaxine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.57 [1.08, 2.29]
4 studies · 807 participants
Moderate

Paroxetine vs venlafaxine

SMD at endpoint · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 411 participants
Moderate

Paroxetine vs venlafaxine

Failure to complete ‐ any cause ‐ · patients with depression

Paroxetine showed no clear difference in failure to complete ‐ any cause ‐ compared with venlafaxine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.08 [0.82, 1.44]
6 studies · 1079 participants
Moderate

Paroxetine vs venlafaxine

Participants with at least some Side Effects · patients with depression

Paroxetine showed no clear difference in participants with at least some Side Effects compared with venlafaxine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.01 [0.52, 1.95]
2 studies · 200 participants
Moderate

Paroxetine vs agomelatine

Participants with at least some Side Effects · patients with depression

Paroxetine showed no clear difference in participants with at least some Side Effects compared with agomelatine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.6 [0.99, 2.59]
1 study · 284 participants
Moderate

Paroxetine vs AMISULPRIDE

Failure to respond at endpoint (6‐12 weeks) · patients with depression

Paroxetine showed no clear difference in failure to respond at endpoint (6‐12 weeks) compared with amisulpride (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.65 [0.36, 1.15]
1 study · 277 participants
Moderate

Paroxetine vs AMISULPRIDE

Failure to respond at 1‐4 weeks · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Paroxetine vs AMISULPRIDE

Failure to respond at 16‐24 weeks · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Paroxetine vs AMISULPRIDE

Failure to remit at endpoint · patients with depression

Paroxetine showed no clear difference in failure to remit at endpoint compared with amisulpride (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.85 [0.49, 1.46]
1 study · 277 participants
Moderate

Paroxetine vs AMISULPRIDE

SMD at endpoint · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 272 participants
Moderate

Paroxetine vs older ADs

Failure to respond at 1‐4 weeks · patients with depression

Paroxetine showed no clear difference in failure to respond at 1‐4 weeks compared with older ADs (low certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.9 [0.61, 1.33]
4 studies · 526 participants
Low

Paroxetine vs AMISULPRIDE

Failure to complete ‐ any cause ‐ · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Paroxetine vs AMISULPRIDE

Participants with at least some Side Effects · patients with depression

Paroxetine showed no clear difference in participants with at least some Side Effects compared with amisulpride (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.49 [0.89, 2.5]
1 study · 277 participants
Moderate