ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask (with frame internal fixation) showed no clear difference in ANB compared with frankel III functional appliance; GRADE not reported.
1 finding from 1 review
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
It is very uncertain whether facemask (RME) or modified facemask changes overjet compared with other non-surgical orthodontic treatments (mini maxillary… (very low certainty).
1 finding from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Bone-anchored intermaxillary traction (BAIMT) led to higher ANB compared with removable mandibular retractor (RMR); GRADE not reported.
1 finding from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Hybrid Hyrax (RME) with miniscrews and Class III elastics showed no clear difference in ANB compared with conventional Hyrax (RME) with miniscrews and Class III elastics; GRADE not reported.
1 finding from 1 review
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Reverse Forsus led to higher overjet compared with untreated control (no treatment); GRADE not reported.
1 finding from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Chin cup (600 g force) showed no clear difference in ANB compared with chin cup (300 g force); GRADE not reported.
1 finding from 1 review
Perceived need for surgery in adulthood · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask may leads to higher perceived need for surgery in adulthood compared with untreated control (no treatment) (low certainty).
1 finding from 1 review
Urologic symptom scores · men with lower urinary tract symptoms secondary to benign prostatic obstruction
Serenoa repens showed no clear difference in urologic symptom scoreMeasured by IPSS scores (range 0 to 35)Higher… compared with placebo or no intervention (high certainty).
1 finding from 1 review
QoL · men with lower urinary tract symptoms secondary to benign prostatic obstruction
Serenoa repens showed no clear difference in quality of lifeMeasured by IPSS‐QoL score (range 0 to 6) compared with placebo or no intervention (high certainty).
1 finding from 1 review
Adverse eventsCumulative incidence · men with lower urinary tract symptoms secondary to benign prostatic obstruction
Serenoa repens showed no clear difference in adverse eventsCumulative incidence compared with placebo or no intervention (moderate certainty).
1 finding from 1 review
Urologic symptom scores · men with lower urinary tract symptoms secondary to benign prostatic obstruction
Serenoa repens in combination with other phytotherapy showed no clear difference in urologic symptom scoreMeasured by IPSS scores (range 0 to 35)Higher… compared with placebo or no intervention (low certainty).
1 finding from 1 review
QoL · men with lower urinary tract symptoms secondary to benign prostatic obstruction
1 finding from 1 review
Adverse eventsCumulative incidence · men with lower urinary tract symptoms secondary to benign prostatic obstruction
Serenoa repens in combination with other phytotherapy showed no clear difference in adverse eventsCumulative incidence compared with placebo or no intervention (low certainty).
1 finding from 1 review
All‐cause mortality: range 1 mo to 1 y · adults admitted to the ICU
It is very uncertain whether higher changes all‐cause mortality: range 1 mo to 1 y compared with lower FiO2 or targets of arterial oxygenation (very low certainty).
1 finding from 1 review
Proportion of participants with 1 or more serious adverse events according to International Conference on Harmonisation Good Clinical Practice (ICH‐GCP) · adults admitted to the ICU
It is very uncertain whether higher changes proportion of participants with ≥ 1 serious adverse events according… compared with lower FiO2 or targets of arterial oxygenation (very low certainty).
1 finding from 1 review
Quality of life (any measure): range 180 d to 1 y · adults admitted to the ICU
1 finding from 1 review
Lung injury diagnosed after randomisation (composite outcome): range 4 d to 23 d · adults admitted to the ICU
It is very uncertain whether higher changes lung injury diagnosed after randomisation (composite outcome): range… compared with lower FiO2 or targets of arterial oxygenation (very low certainty).
1 finding from 1 review
Myocardial infarction · adults admitted to the ICU
It is very uncertain whether higher changes myocardial infarction diagnosed after randomisation: range ≤ 90 d compared with lower FiO2 or targets of arterial oxygenation (very low certainty).
1 finding from 1 review
Stroke · adults admitted to the ICU
It is very uncertain whether higher changes stroke diagnosed after randomisation: range 1 mo to 3 mo compared with lower FiO2 or targets of arterial oxygenation (very low certainty).
1 finding from 1 review
Sepsis diagnosed after randomisation: range 28 d to 60 d · adults admitted to the ICU
It is very uncertain whether higher changes sepsis diagnosed after randomisation: range 28 d to 60 d compared with lower FiO2 or targets of arterial oxygenation (very low certainty).
1 finding from 1 review