Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,640 questions · 2,709 findings · 446 reviews

No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

Imiquimod vs vehicle

Long‐term clinical cure (beyond 6 months after start of treatment) (completely cleared long term) · molluscum contagiosum

Imiquimod showed no clear difference in long‐term clinical cure (beyond 6 months after start of treatment)… compared with vehicle (moderate certainty).

1 finding from 1 review

CLOZAPINE + RISPERIDONE vs CLOZAPINE + ZIPRASIDONE (Kuwilsky 2010)

Acceptability of treatment ‐ leaving the study early · people with treatment‐resistant schizophrenia

It is very uncertain whether CLOZAPINE + RISPERIDONE changes leaving the study early: acceptability of treatment ‐ as measured by… compared with CLOZAPINE + ZIPRASIDONE (Kuwilsky 2010) (very low certainty).

1 finding from 1 review

CLOZAPINE + ARIPIPRAZOLE vs CLOZAPINE + HALOPERIDOL (Cipriani 2013)

Acceptability of treatment ‐ leaving the study early · people with treatment‐resistant schizophrenia

It is very uncertain whether CLOZAPINE + ARIPIPRAZOLE changes leaving the study early: acceptability of treatment ‐ as measured by… compared with CLOZAPINE + HALOPERIDOL (Cipriani 2013) (very low certainty).

1 finding from 1 review

Retroperitoneal drainage vs no drainage after pelvic lymphadenectomy

Long‐term lymphocyst formation: both asymptomatic and symptomatic at 12 months after surgery · patients with gynaecological malignancies

Retroperitoneal drainage showed no clear difference in long‐term lymphocyst formation: both asymptomatic and symptomatic at… compared with no drainage after pelvic lymphadenectomy (high certainty).

1 finding from 1 review

Retroperitoneal drainage vs no drainage after pelvic lymphadenectomy

Long‐term lymphocyst formation: symptomatic at 12 months after surgery · patients with gynaecological malignancies

Retroperitoneal drainage showed no clear difference in long‐term lymphocyst formation: symptomatic at 12 months after surgery compared with no drainage after pelvic lymphadenectomy (low certainty).

1 finding from 1 review

INTENSIVE CASE MANAGEMENT vs usual care

Adverse event: 1b. Death ‐ suicide ‐ by long term · people with severe mental disorders

Intensive Case Management showed no clear difference in adverse event: 1b. Death ‐ suicide ‐ by long term compared with standard care (low certainty).

1 finding from 1 review