PCP‐related mortality Clinical only · patients with Pneumocystis pneumonia (PCP) in non‐HIV immunocompromised patients
TMP/SMX may leads to lower PCP‐related mortality Clinical only compared with placebo, no treatment or non‐PCP drug (low certainty).
1 finding from 1 review
Abnormal Involuntary Movement Scale LOCF at week 12 A physician‐administered rating scale with 12 items to measure tardive dyskinesia Scale from 0 to 40 · patients with an acute manic or mixed episode
1 finding from 1 review
no estimate extracted
634 participants
Low
Mean change in YMRS from baseline at three weeks Young Mania Rating Scale (YMRS): an 11‐item questionnaire to assess the severity of core symptoms of mania. Scale from 0 to 60 · patients with an acute manic or mixed episode
1 finding from 1 review
no estimate extracted
972 participants
Moderate
≥ 50% decrease in total YMRS from baseline at three weeks Young Mania Rating Scale (as above) · patients with an acute manic or mixed episode
Aripiprazole showed no clear difference in ≥ 50% decrease in YMRS from baseline at week three Young Mania… compared with other drug treatment (moderate certainty).
1 finding from 1 review
RR 1.12 [0.77, 1.63]
990 participants
Moderate
Numbers completing the trial (at end of week three) Number of participants · patients with an acute manic or mixed episode
Aripiprazole may leads to higher numbers completing the trial (at end of week three) Number of… compared with other drug treatment (low certainty).
1 finding from 1 review
RR 1.13 [1.03, 1.24]
994 participants
Low
Teacher rating ADHD overall scale Abbreviated Parent‐Teacher Questionnaire (Conner, 1973) · patients with attention deficit /hyperactivity disorder
1 finding from 1 review
Recurrent seizure at 6 months · children with febrile seizures
Intermittent oral or rectal diazepam probably leads to lower recurrent seizure at 6 months compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Recurrent seizure at 18 months · children with febrile seizures
Continuous phenobarbital showed no clear difference in recurrent seizure at 18 months compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Recurrent seizure at 24 months · children with febrile seizures
Continuous phenobarbital probably leads to lower recurrent seizure at 24 months compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Recurrent seizure at 36 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 48 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 60 months or greater · children with febrile seizures
It is very uncertain whether continuous phenobarbital changes recurrent seizure at 60 months or greater compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Recurrent seizure at 6 months · children with febrile seizures
It is very uncertain whether intermittent phenobarbital changes recurrent seizure at 6 months compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Recurrent seizure at 12 months · children with febrile seizures
Intermittent phenobarbital showed no clear difference in recurrent seizure at 12 months compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Recurrent seizure at 18 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 24 months · children with febrile seizures
Intermittent phenobarbital showed no clear difference in recurrent seizure at 24 months compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrent seizure at 36 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 12 months · children with febrile seizures
Intermittent oral or rectal diazepam probably leads to lower recurrent seizure at 12 months compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Recurrent seizure at 48 months · children with febrile seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrent seizure at 60 months or greater · children with febrile seizures
It is very uncertain whether intermittent phenobarbital changes recurrent seizure at 60 months or greater compared with placebo or no treatment (very low certainty).
1 finding from 1 review