Findings

What do systematic reviews say?

1,266 questions · 1,314 findings · 160 reviews · Headline outcomes only

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No studies found 309 · 23.5%GRADE not reported 34 · 2.6%Very low 356 · 27.1%Low 393 · 29.9%Moderate 187 · 14.2%High 35 · 2.7%

Esomeprazole vs fluticasone

Clinical improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs fluticasone

Clinical improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 67 participants
Very low

Esomeprazole vs fluticasone

Histological improvement (dichotomous) · active EoE patients

It is very uncertain whether esomeprazole changes histological improvement at 8 weeks (dichotomous) compared with fluticasone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.62 [0.77, 3.41]
2 studies · 72 participants
Very low

Esomeprazole vs fluticasone

Histological improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 70 participants
Very low

Esomeprazole vs fluticasone

Endoscopic improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs fluticasone

Endoscopic improvement (continuous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs fluticasone

Withdrawals due to adverse events · active EoE patients

It is very uncertain whether esomeprazole changes withdrawals due to adverse events at 8 weeks compared with fluticasone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.95 [0.07, 13.38]
2 studies · 72 participants
Very low

One‐food elimination diet vs four‐food elimination diet

Clinical improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs four‐food elimination diet

Clinical improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

One‐food elimination diet vs four‐food elimination diet

Histological improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether one‐food elimination diet changes histological improvement at 12 weeks (dichotomous) compared with four‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 2.26 [1.15, 4.43]
1 study · 63 participants
Very low

Corticosteroids vs placebo

Endoscopic improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 596 participants
Low

One‐food elimination diet vs four‐food elimination diet

Histological improvement (continuous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs four‐food elimination diet

Endoscopic improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs four‐food elimination diet

Endoscopic improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

One‐food elimination diet vs four‐food elimination diet

Withdrawals due to adverse events · active EoE pediatric patients

It is very uncertain whether one‐food elimination diet changes withdrawals due to adverse events at 12 weeks compared with four‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.33 [0.11, 0.98]
1 study · 63 participants
Very low

One‐food elimination diet vs six‐food elimination diet

Clinical improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs six‐food elimination diet

Clinical improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 129 participants
Very low

One‐food elimination diet vs six‐food elimination diet

Histological improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether one‐food elimination diet changes histological improvement at 6 weeks (dichotomous) compared with six‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.85 [0.54, 1.33]
1 study · 129 participants
Very low

One‐food elimination diet vs six‐food elimination diet

Histological improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 129 participants
Very low

One‐food elimination diet vs six‐food elimination diet

Endoscopic improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found