Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,103 questions · 1,157 findings · 177 reviews · Headline outcomes only

No studies found 291 · 25.2%GRADE not reported 85 · 7.3%Very low 317 · 27.4%Low 258 · 22.3%Moderate 169 · 14.6%High 37 · 3.2%

Medical vs open surgical PD catheter insertion

Early PD catheter function (within 4 weeks of PD catheter insertion) · improving catheter function and clinical outcomes in PD patients

Medical showed no clear difference in early PD catheter function (within 4 weeks of PD catheter insertion) compared with open surgical PD catheter insertion (low certainty).

1 finding from 1 review

Medical vs open surgical PD catheter insertion

Late PD catheter failure (> 4 weeks following PD catheter insertion) · improving catheter function and clinical outcomes in PD patients

It is very uncertain whether medical changes late PD catheter failure (> 4 weeks following PD catheter insertion) compared with open surgical PD catheter insertion (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa vs invagination pancreaticojejunostomy

Rate of POPF (grade B or C defined according to the 2005 ISGPF definition) · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa changes rate of POPF (grade B or C defined according to the 2005 ISGPF… compared with invagination pancreaticojejunostomy (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart technique vs duct‐to‐mucosa pancreaticojejunostomy using the traditional interrupted technique

Adverse events · adults undergoing open pancreaticoduodenectomy

The review found no eligible studies for this question.

1 finding from 1 review

Duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart technique vs duct‐to‐mucosa pancreaticojejunostomy using the traditional interrupted technique

Rate of surgical reintervention · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart… changes rate of surgical reintervention compared with duct‐to‐mucosa pancreaticojejunostomy using the traditional… (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart technique vs duct‐to‐mucosa pancreaticojejunostomy using the traditional interrupted technique

Rate of postoperative bleeding · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart… changes rate of postoperative bleeding compared with duct‐to‐mucosa pancreaticojejunostomy using the traditional… (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart technique vs duct‐to‐mucosa pancreaticojejunostomy using the traditional interrupted technique

Overall rate of surgical complications · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart… changes overall rate of surgical complications compared with duct‐to‐mucosa pancreaticojejunostomy using the traditional… (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart technique vs duct‐to‐mucosa pancreaticojejunostomy using the traditional interrupted technique

Quality of life · adults undergoing open pancreaticoduodenectomy

The review found no eligible studies for this question.

1 finding from 1 review

Duct‐to‐mucosa vs invagination pancreaticojejunostomy

Postoperative mortality · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa changes postoperative mortality compared with invagination pancreaticojejunostomy (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa vs invagination pancreaticojejunostomy

Rate of surgical reintervention · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa changes rate of surgical reintervention compared with invagination pancreaticojejunostomy (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa vs invagination pancreaticojejunostomy

Rate of postoperative bleeding · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa changes rate of postoperative bleeding compared with invagination pancreaticojejunostomy (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa vs invagination pancreaticojejunostomy

Overall rate of surgical complications · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa changes overall rate of surgical complications compared with invagination pancreaticojejunostomy (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa vs invagination pancreaticojejunostomy

Length of hospital stay · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa changes length of hospital stay (days) compared with invagination pancreaticojejunostomy (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa pancreaticojejunostomy using the modified Blumgart technique vs duct‐to‐mucosa pancreaticojejunostomy using the traditional interrupted technique

Rate of POPF (grade B or C defined according to the 2016 ISGPS definition) · adults undergoing open pancreaticoduodenectomy
1 finding from 1 review

Endometrial resection or ablation vs open hysterectomy

Effectiveness Proportion of women with perception of improvement of bleeding symptoms · HMB

Endometrial resection or ablation probably leads to lower effectiveness Woman's perception (proportion with improvement in… compared with open hysterectomy (moderate certainty).

1 finding from 1 review