evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

88 questions · 90 findings · 13 reviews · Skin

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 11 · 12.2%GRADE not reported 4 · 4.4%Very low 27 · 30%Low 32 · 35.6%Moderate 14 · 15.6%High 2 · 2.2%

Chemical peeling vs combined chemical peeling plus any active intervention

Participant‐assessed adverse events (short‐term) N of participants with adverse events · people with acne scars

It is very uncertain whether chemical peeling changes participant‐assessed adverse events (short‐term) N of participants… compared with combined chemical peeling plus any active intervention (very low certainty).

1 finding from 1 review

Fractional laser vs non‐fractional non‐ablative laser

Adverse events ‐ hyperpigmentation ( · people with acne scars

It is very uncertain whether fractional laser changes investigator‐assessed adverse events (short‐term) Hyperpigmentation… compared with non‐fractional non‐ablative laser (very low certainty).

1 finding from 1 review

Chemical peeling vs needling

Participant‐reported scar improvement (short‐term) N of participants with > 50% improvement in acne scars · people with acne scars

It is very uncertain whether chemical peeling changes participant‐reported scar improvement (short‐term) N of participants… compared with needling (very low certainty).

1 finding from 1 review

Chemical peeling vs needling

Investigator‐assessed adverse events (short‐term) · people with acne scars

Chemical peeling showed no clear difference in investigator‐assessed adverse events (short‐term) N of participants… compared with needling (low certainty).

1 finding from 1 review

Chemical peeling vs needling

Participant‐assessed adverse events (short‐term) N of participants with positive adverse events · people with acne scars

It is very uncertain whether chemical peeling changes participant‐assessed adverse events (short‐term) N of participants… compared with needling (very low certainty).

1 finding from 1 review

Injectable fillers vs placebo or no treatment

Participant‐reported scar improvement (short‐term) N of participants with > 50% improvement in acne scars · people with acne scars

Injectable fillers probably leads to higher participant‐reported scar improvement (short‐term) N of participants… compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Fractional laser vs non‐fractional non‐ablative laser

Participant‐assessed adverse events (short‐term) Burning N of participants with adverse events · people with acne scars

It is very uncertain whether fractional laser changes participant‐assessed adverse events (short‐term) Burning N of… compared with non‐fractional non‐ablative laser (very low certainty).

1 finding from 1 review

Injectable fillers vs placebo or no treatment

Participant‐assessed adverse events (short‐term) N of participants with positive adverse events · people with acne scars

Injectable fillers showed no clear difference in participant‐reported adverse events (short‐term) N of participants… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Injectable fillers vs placebo or no treatment

Investigator‐assessed adverse events (short‐term) N of participants with positive adverse events · people with acne scars

Injectable fillers showed no clear difference in investigator‐assessed adverse events (short‐term) N of participants… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Fractional laser vs radiofrequency

Participant‐reported scar improvement (short‐term) N of participants with > 50% improvement in acne scars · people with acne scars

It is very uncertain whether fractional laser changes participant‐reported scar improvement (short‐term) N of participants… compared with radiofrequency (very low certainty).

1 finding from 1 review

Fractional laser vs radiofrequency

Investigator‐assessed adverse events (short‐term) · people with acne scars

The review found no eligible studies for this question.

1 finding from 1 review

Herbal medicines vs antibiotics alone

Remission · participants with acne

Herbal medicine showed no clear difference in secondary outcome: number of participants with remission (ITT‐best… compared with antibiotics (low certainty).

2 findings from 1 review

Tacrolimus 0.1% vs corticosteroids

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.1% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).

1 finding from 1 review

Loratadine 10 mg vs hydroxyzine 25 mg

Complete suppression of urticaria: short‐term duration of intervention Global assessment of symptom scores · patients with chronic spontaneous urticaria

Loratadine 10 mg showed no clear difference in complete suppression of urticaria: short‐term duration of… compared with hydroxyzine 25 mg (low certainty).

1 finding from 1 review